BS9246

antibody from Bioworld Technology, Inc
Targeting: ADCY9 AC9
Provider product page for BS9246
Western blot
Immunohistochemistry

Antibody data

Product number
BS9246 - Provider product page
Provider
Bioworld Technology, Inc
Product name
A Cyclase IX (P974) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 971-1020 of Human A Cyclase IX.
Description
Classically, adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor (i.e., Ï« ÉÇ-adrenergic receptor) catalyzes the exchange of GDP (bound to GÏ« s) for GTP, dissociation of GTP-GÏ« s from Gbg and GÏ« s-mediated activation of adenylyl cyclase. The most abundant cerebral adenylyl cyclases appears to be adenylyl cyclase IX. AC IX is confined to the gray matter and its expression is mainly neuronal, with its highest expression located at the hippocampus. ACIX is also expressed in heart, pancreas and thyrocytes. AC I and AC IX are regulated reciprocally by intracellular free Ca2+. The inhibition of AC IX by Ca2+ is blocked by the calcineurin inhibitors FK506 and cyclosporin A.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ADCY9 protein structure - BS9246 shown in red.