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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [5]
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- Product number
- PA5-60876 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- HMCES Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: WRLLTMAGIF DCWEPPEGGD VLYSYTIITV DSCKGLSDIH HRMPAILDGE EAVSKWLDFG EVSTQEALKL IHPTENITFH AVSSVVNNS Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.2 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability.
Kharat SS, Ding X, Swaminathan D, Suresh A, Singh M, Sengodan SK, Burkett S, Marks H, Pamala C, He Y, Fox SD, Buehler EC, Muegge K, Martin SE, Sharan SK
Science signaling 2020 Aug 18;13(645)
Science signaling 2020 Aug 18;13(645)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of HMCES in human cell line U-2 OS shows positivity in nucleus. Samples were probed using a HMCES Polyclonal Antibody (Product # PA5-60876).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of HMCES in human Fallopian tube using HMCES Polyclonal Antibody (Product # PA5-60876) shows strong nuclear positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of HMCES in human skeletal muscle using HMCES Polyclonal Antibody (Product # PA5-60876) shows no positivity in myocytes as expected.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of HMCES in human tonsil using HMCES Polyclonal Antibody (Product # PA5-60876) shows strong nuclear positivity in germinal center cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of HMCES in human testis using HMCES Polyclonal Antibody (Product # PA5-60876) shows strong nuclear positivity in cells in seminiferous ducts.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of HMCES in human testis using a HMCES Polyclonal Antibody (Product # PA5-60876) shows strong nuclear positivity in cells in seminiferous ducts.
