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- References [24]
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- Product number
- 16409-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16409-1-AP, RRID:AB_10804656
- Product name
- Biglycan antibody
- Antibody type
- Polyclonal
- Description
- Biglycan antibody (Cat. #16409-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, pig and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of ROS and KEAP1-related genes and verified targets of α-hederin induce cell death for CRC.
The role of vitamin D receptor in predentin mineralization and dental repair after injury.
Dermal papilla cell-secreted biglycan regulates hair follicle phase transit and regeneration by activating Wnt/β-catenin.
Proteomic analysis of decellularized mice liver and kidney extracellular matrices.
Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain.
Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy.
Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.
Establishment of a risk model by integrating hypoxia genes in predicting prognosis of esophageal squamous cell carcinoma.
Stroma biglycan expression can be a prognostic factor in prostate cancers.
Dissecting the role of cancer-associated fibroblast-derived biglycan as a potential therapeutic target in immunotherapy resistance: A tumor bulk and single-cell transcriptomic study.
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis.
Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells.
Landscape of cancer-associated fibroblasts identifies the secreted biglycan as a protumor and immunosuppressive factor in triple-negative breast cancer.
Expression and localization of CD63 in the intracellular vesicles of odontoblasts.
Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer Cells.
Effects of aging on the histology and biochemistry of rat tendon healing.
Biglycan, tumor endothelial cell secreting proteoglycan, as possible biomarker for lung cancer.
Quantitative Proteome of Infant Stenotic Ureters Reveals Extracellular Matrix Organization and Oxidative Stress Dysregulation Underlying Ureteropelvic Junction Obstruction.
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Expression and localization of the small proteoglycans decorin and biglycan in articular cartilage of Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency.
Biglycan-mediated upregulation of MHC class I expression in HER-2/neu-transformed cells.
Wang G, Zhu ZM, Wang K
Drug development research 2024 May;85(3):e22200
Drug development research 2024 May;85(3):e22200
The role of vitamin D receptor in predentin mineralization and dental repair after injury.
Liu Y, Wu Y, Hu X, Sun Y, Zeng G, Wang Q, Liu S, Sun M
Cell and tissue research 2024 Jun;396(3):343-351
Cell and tissue research 2024 Jun;396(3):343-351
Dermal papilla cell-secreted biglycan regulates hair follicle phase transit and regeneration by activating Wnt/β-catenin.
Zhu N, Yan J, Gu W, Yang Q, Lin E, Lu S, Cai B, Xia B, Liu X, Lin C
Experimental dermatology 2024 Jan;33(1):e14969
Experimental dermatology 2024 Jan;33(1):e14969
Proteomic analysis of decellularized mice liver and kidney extracellular matrices.
Diedrich AM, Daneshgar A, Tang P, Klein O, Mohr A, Onwuegbuchulam OA, von Rueden S, Menck K, Bleckmann A, Juratli MA, Becker F, Sauer IM, Hillebrandt KH, Pascher A, Struecker B
Journal of biological engineering 2024 Feb 22;18(1):17
Journal of biological engineering 2024 Feb 22;18(1):17
Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain.
Sunderland A, Williams J, Andreou T, Rippaus N, Fife C, James F, Kartika YD, Speirs V, Carr I, Droop A, Lorger M
Frontiers in oncology 2023;13:1191980
Frontiers in oncology 2023;13:1191980
Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy.
Vaxevanis CK, Bauer M, Subbarayan K, Friedrich M, Massa C, Biehl K, Al-Ali HK, Wickenhauser C, Seliger B
Oncoimmunology 2023;12(1):2152998
Oncoimmunology 2023;12(1):2152998
Multi-Proteomic Analysis Reveals the Effect of Protein Lactylation on Matrix and Cholesterol Metabolism in Tendinopathy.
Lin Y, Chen M, Wang D, Yu Y, Chen R, Zhang M, Yu H, Huang X, Rao M, Wang Y, Li Y, Yan J, Yin P
Journal of proteome research 2023 Jun 2;22(6):1712-1722
Journal of proteome research 2023 Jun 2;22(6):1712-1722
Establishment of a risk model by integrating hypoxia genes in predicting prognosis of esophageal squamous cell carcinoma.
Xiao W, Tang P, Sui Z, Han Y, Zhao G, Wu X, Yang Y, Zhu N, Gong L, Yu Z, Zhang H
Cancer medicine 2023 Jan;12(2):2117-2133
Cancer medicine 2023 Jan;12(2):2117-2133
Stroma biglycan expression can be a prognostic factor in prostate cancers.
Furumido J, Maishi N, Yanagawa-Matsuda A, Kikuchi H, Matsumoto R, Osawa T, Abe T, Matsuno Y, Shinohara N, Hida Y, Hida K
International journal of urology : official journal of the Japanese Urological Association 2023 Feb;30(2):147-154
International journal of urology : official journal of the Japanese Urological Association 2023 Feb;30(2):147-154
Dissecting the role of cancer-associated fibroblast-derived biglycan as a potential therapeutic target in immunotherapy resistance: A tumor bulk and single-cell transcriptomic study.
Zheng S, Liang JY, Tang Y, Xie J, Zou Y, Yang A, Shao N, Kuang X, Ji F, Liu X, Tian W, Xiao W, Lin Y
Clinical and translational medicine 2023 Feb;13(2):e1189
Clinical and translational medicine 2023 Feb;13(2):e1189
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S
BMC cancer 2023 Apr 6;23(1):323
BMC cancer 2023 Apr 6;23(1):323
Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1.
Lu J, Yang X, He C, Chen Y, Li C, Li S, Chen Y, Wu Y, Xiang Z, Kang J, Jiang G, Wang C, Diarra MD, He R, Feng G, Yan R
Acta biomaterialia 2023 Apr 15;161:80-99
Acta biomaterialia 2023 Apr 15;161:80-99
Identification of key genes and pathways revealing the central regulatory mechanism of brain-derived glucagon-like peptide-1 on obesity using bioinformatics analysis.
Shao Y, Tian J, Yang Y, Hu Y, Zhu Y, Shu Q
Frontiers in neuroscience 2022;16:931161
Frontiers in neuroscience 2022;16:931161
Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells.
Subbarayan K, Massa C, Leisz S, Steven A, Bethmann D, Biehl K, Wickenhauser C, Seliger B
Oncoimmunology 2022;11(1):2069214
Oncoimmunology 2022;11(1):2069214
Landscape of cancer-associated fibroblasts identifies the secreted biglycan as a protumor and immunosuppressive factor in triple-negative breast cancer.
Zheng S, Zou Y, Tang Y, Yang A, Liang JY, Wu L, Tian W, Xiao W, Xie X, Yang L, Xie J, Wei W, Xie X
Oncoimmunology 2022;11(1):2020984
Oncoimmunology 2022;11(1):2020984
Expression and localization of CD63 in the intracellular vesicles of odontoblasts.
Matsuki-Fukushima M, Fujikawa K, Inoue S, Nakamura M
Histochemistry and cell biology 2022 Jun;157(6):611-622
Histochemistry and cell biology 2022 Jun;157(6):611-622
Biglycan Promotes Cancer Stem Cell Properties, NFκB Signaling and Metastatic Potential in Breast Cancer Cells.
Manupati K, Paul R, Hao M, Haas M, Bian ZC, Holm TM, Guan JL, Yeo SK
Cancers 2022 Jan 17;14(2)
Cancers 2022 Jan 17;14(2)
Effects of aging on the histology and biochemistry of rat tendon healing.
Lai F, Tang H, Wang J, Lu K, Bian X, Wang Y, Shi Y, Guo Y, He G, Zhou M, Zhang X, Zhou B, Zhang J, Chen W, Tang K
BMC musculoskeletal disorders 2021 Nov 15;22(1):949
BMC musculoskeletal disorders 2021 Nov 15;22(1):949
Biglycan, tumor endothelial cell secreting proteoglycan, as possible biomarker for lung cancer.
Morimoto H, Hida Y, Maishi N, Nishihara H, Hatanaka Y, Li C, Matsuno Y, Nakamura T, Hirano S, Hida K
Thoracic cancer 2021 May;12(9):1347-1357
Thoracic cancer 2021 May;12(9):1347-1357
Quantitative Proteome of Infant Stenotic Ureters Reveals Extracellular Matrix Organization and Oxidative Stress Dysregulation Underlying Ureteropelvic Junction Obstruction.
Li Y, Chen Z, Zhang J, Zhang Q, He L, Xu M, Xu G, Geng H, Fang X
Proteomics. Clinical applications 2020 Nov;14(6):e2000030
Proteomics. Clinical applications 2020 Nov;14(6):e2000030
Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway.
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, Zhu M, Zhou M, Yang M, Mu M, Chen W, Zhou B, Zhang J, Tang K
Cell proliferation 2019 Jul;52(4):e12650
Cell proliferation 2019 Jul;52(4):e12650
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Cui Q, Xing J, Yu M, Wang Y, Xu J, Gu Y, Nan X, Ma W, Liu H, Zhao H
Cell death & disease 2019 Feb 20;10(3):172
Cell death & disease 2019 Feb 20;10(3):172
Expression and localization of the small proteoglycans decorin and biglycan in articular cartilage of Kashin-Beck disease and rats induced by T-2 toxin and selenium deficiency.
Wang M, Xue S, Fang Q, Zhang M, He Y, Zhang Y, Lammi MJ, Cao J, Chen J
Glycoconjugate journal 2019 Dec;36(6):451-459
Glycoconjugate journal 2019 Dec;36(6):451-459
Biglycan-mediated upregulation of MHC class I expression in HER-2/neu-transformed cells.
Subbarayan K, Leisz S, Wickenhauser C, Bethmann D, Massa C, Steven A, Seliger B
Oncoimmunology 2018;7(4):e1373233
Oncoimmunology 2018;7(4):e1373233
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 16409-1-AP(BGN antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human renal cell carcinoma using 16409-1-AP(BGN antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human renal cell carcinoma using 16409-1-AP(BGN antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Biglycan antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Biglycan. This antibody recognizes human,mouse,rat antigen. The Biglycan antibody has been validated for the following applications: ELISA, WB, IHC analysis.
