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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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- Product number
- PA5-65143 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- ZRANB3 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: AVDNEGNPLCL RCQQPTCQTK QACKANSWDS RFCSLKCQEE FWIRSNNSYL RAKVFETEHG VCQLCNVNAQ ELFLRLRDAP KSQRKNLLYA TWT Highest antigen sequence identity to the following orthologs - mouse 80%, rat 82%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.10 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through PCNA-dependent CAF-1 recycling.
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
Thakar T, Dhoonmoon A, Straka J, Schleicher EM, Nicolae CM, Moldovan GL
Nature communications 2022 Sep 9;13(1):5323
Nature communications 2022 Sep 9;13(1):5323
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cells.
Jackson LM, Dhoonmoon A, Hale A, Dennis KA, Schleicher EM, Nicolae CM, Moldovan GL
Nucleic acids research 2021 Dec 16;49(22):12855-12869
Nucleic acids research 2021 Dec 16;49(22):12855-12869
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Immunofluorescent staining of ZRANB3 in human cell line MCF7 shows localization to nucleus. Samples were probed using a ZRANB3 Polyclonal Antibody (Product # PA5-65143).
