Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7798 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-IL3RA Monoclonal antibody, clone 7I7 [APC]
- Antibody type
- Monoclonal
- Description
- IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. It is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. It is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
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