BS6993

antibody from Bioworld Technology, Inc
Targeting: CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR
Provider product page for BS6993
Western blot
Immunohistochemistry

Antibody data

Product number
BS6993 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CXCR 3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CXCR-3.
Description
The CXC or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemo-attractants for neutrophils. The CXC family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 or SDF-1. SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes but not neutrophils. Receptors for the CXC family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (variously referred to as LESTR or CXCR-4). CXCR-3, also known as IP-10/Mig receptor, mediates Ca++ mobilization and chemotaxis in response to the CXC chemo-kines IP-10 and Mig. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CXCR3 protein structure - BS6993 shown in red.