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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB1685P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse CXCR3 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse CXCR3.
- Reactivity
- Mouse
- Host
- Rat
- Antigen sequence
AAC40163- Isotype
- IgG
- Antibody clone number
- 220803
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.
Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation.
Expression of CXCL4 in microglia in vitro and in vivo and its possible signaling through CXCR3.
Both Th1 and Th17 are immunopathogenic but differ in other key biological activities.
Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.
CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system.
Arieta Kuksin C, Gonzalez-Perez G, Minter LM
Blood 2015 Mar 26;125(13):2087-94
Blood 2015 Mar 26;125(13):2087-94
Thymic self-reactivity selects natural interleukin 17-producing T cells that can regulate peripheral inflammation.
Marks BR, Nowyhed HN, Choi JY, Poholek AC, Odegard JM, Flavell RA, Craft J
Nature immunology 2009 Oct;10(10):1125-32
Nature immunology 2009 Oct;10(10):1125-32
Expression of CXCL4 in microglia in vitro and in vivo and its possible signaling through CXCR3.
de Jong EK, de Haas AH, Brouwer N, van Weering HR, Hensens M, Bechmann I, Pratley P, Wesseling E, Boddeke HW, Biber K
Journal of neurochemistry 2008 Jun;105(5):1726-36
Journal of neurochemistry 2008 Jun;105(5):1726-36
Both Th1 and Th17 are immunopathogenic but differ in other key biological activities.
Cox CA, Shi G, Yin H, Vistica BP, Wawrousek EF, Chan CC, Gery I
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7414-22
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7414-22
Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
Miyazaki Y, Shimanoe Y, Wang S, Yoshida H
Biochemical and biophysical research communications 2008 Aug 29;373(3):397-402
Biochemical and biophysical research communications 2008 Aug 29;373(3):397-402
E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.
Horikawa M, Fujimoto M, Hasegawa M, Matsushita T, Hamaguchi Y, Kawasuji A, Matsushita Y, Fujita T, Ogawa F, Takehara K, Steeber DA, Sato S
The American journal of pathology 2006 Sep;169(3):740-9
The American journal of pathology 2006 Sep;169(3):740-9
CXCL10 is the key ligand for CXCR3 on CD8+ effector T cells involved in immune surveillance of the lymphocytic choriomeningitis virus-infected central nervous system.
Christensen JE, de Lemos C, Moos T, Christensen JP, Thomsen AR
Journal of immunology (Baltimore, Md. : 1950) 2006 Apr 1;176(7):4235-43
Journal of immunology (Baltimore, Md. : 1950) 2006 Apr 1;176(7):4235-43
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CXCR3 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse CD3 APC-conjugated Monoclonal Antibody (Catalog # FAB4841A) and either (A) Rat Anti-Mouse CXCR3 PE-conjugated Monoclonal Antibody (Catalog # FAB1685P) or (B) Rat IgG2A Phycoerythrin Isotype Control (Catalog # IC006P). View our protocol for Staining Membrane-associated Proteins.
