Antibody data
- Antibody Data
- Antigen structure
- References [25]
- Comments [0]
- Validations
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- FAB160P-025 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CXCR3 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human CXCR3.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P49682
- Isotype
- IgG
- Antibody clone number
- 49801
- Vial size
- 25 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Endothelial cell functions impaired by interferon in vitro: Insights into the molecular mechanism of thrombotic microangiopathy associated with interferon therapy.
Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis.
IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential.
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells.
Human trophectoderm apposition is regulated by interferon γ-induced protein 10 (IP-10) during early implantation.
Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome.
IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Endometrial NK cells are special immature cells that await pregnancy.
Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients.
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.
Distinct chemokine triggers and in vivo migratory paths of fluorescein dye-labeled T Lymphocytes in acutely simian immunodeficiency virus SIVmac251-infected and uninfected macaques.
Chemokine networks and in vivo T-lymphocyte trafficking in nonhuman primates.
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Jia H, Thelwell C, Dilger P, Bird C, Daniels S, Wadhwa M
Thrombosis research 2018 Mar;163:105-116
Thrombosis research 2018 Mar;163:105-116
Autosomal dominant gain of function STAT1 mutation and severe bronchiectasis.
Breuer O, Daum H, Cohen-Cymberknoh M, Unger S, Shoseyov D, Stepensky P, Keller B, Warnatz K, Kerem E
Respiratory medicine 2017 May;126:39-45
Respiratory medicine 2017 May;126:39-45
IL-12 directs further maturation of ex vivo differentiated NK cells with improved therapeutic potential.
Lehmann D, Spanholtz J, Sturtzel C, Tordoir M, Schlechta B, Groenewegen D, Hofer E
PloS one 2014;9(1):e87131
PloS one 2014;9(1):e87131
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation.
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Journal of immunology (Baltimore, Md. : 1950) 2014 Mar 15;192(6):2634-42
Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells.
Liu C, Pham K, Luo D, Reynolds BA, Hothi P, Foltz G, Harrison JK
PloS one 2013;8(3):e59750
PloS one 2013;8(3):e59750
Human trophectoderm apposition is regulated by interferon γ-induced protein 10 (IP-10) during early implantation.
Sela HY, Goldman-Wohl DS, Haimov-Kochman R, Greenfield C, Natanson-Yaron S, Hamani Y, Revel A, Lavy Y, Singer O, Yachimovich-Cohen N, Turetsky T, Mandelboim O, Reubinoff B, Yagel S
Placenta 2013 Mar;34(3):222-30
Placenta 2013 Mar;34(3):222-30
Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
Cerdeira AS, Rajakumar A, Royle CM, Lo A, Husain Z, Thadhani RI, Sukhatme VP, Karumanchi SA, Kopcow HD
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 15;190(8):3939-48
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 15;190(8):3939-48
Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis.
Badr G, Lefevre EA, Mohany M
PloS one 2011;6(9):e23741
PloS one 2011;6(9):e23741
Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis.
Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
Clinical and experimental immunology 2011 Feb;163(2):215-24
Clinical and experimental immunology 2011 Feb;163(2):215-24
Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.
Oo YH, Weston CJ, Lalor PF, Curbishley SM, Withers DR, Reynolds GM, Shetty S, Harki J, Shaw JC, Eksteen B, Hubscher SG, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2886-98
CD56highCD16-CD62L- NK cells accumulate in allergic contact dermatitis and contribute to the expression of allergic responses.
Carbone T, Nasorri F, Pennino D, Eyerich K, Foerster S, Cifaldi L, Traidl-Hoffman C, Behrendt H, Cavani A
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Journal of immunology (Baltimore, Md. : 1950) 2010 Jan 15;184(2):1102-10
Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome.
Yoon KC, Park CS, You IC, Choi HJ, Lee KH, Im SK, Park HY, Pflugfelder SC
Investigative ophthalmology & visual science 2010 Feb;51(2):643-50
Investigative ophthalmology & visual science 2010 Feb;51(2):643-50
IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A
The Journal of allergy and clinical immunology 2009 Jan;123(1):59-66.e4
The Journal of allergy and clinical immunology 2009 Jan;123(1):59-66.e4
Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions.
Pokkali S, Das SD, R L
Cytokine 2008 Mar;41(3):307-14
Cytokine 2008 Mar;41(3):307-14
CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.
Nonomura C, Kikuchi J, Kiyokawa N, Ozaki H, Mitsunaga K, Ando H, Kanamori A, Kannagi R, Fujimoto J, Muroi K, Furukawa Y, Nakamura M
Cancer research 2008 Feb 1;68(3):790-9
Cancer research 2008 Feb 1;68(3):790-9
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals.
Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, O'Shea MA, Roby G, Kottilil S, Arthos J, Proschan MA, Chun TW, Fauci AS
The Journal of experimental medicine 2008 Aug 4;205(8):1797-805
The Journal of experimental medicine 2008 Aug 4;205(8):1797-805
Chemokine production and chemokine receptor expression by human glioma cells: role of CXCL10 in tumour cell proliferation.
Maru SV, Holloway KA, Flynn G, Lancashire CL, Loughlin AJ, Male DK, Romero IA
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Journal of neuroimmunology 2008 Aug 13;199(1-2):35-45
Endometrial NK cells are special immature cells that await pregnancy.
Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients.
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G, Petzelbauer P, Rot A, Maurer D
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):4272-82
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):4272-82
Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.
Muller A, Sonkoly E, Eulert C, Gerber PA, Kubitza R, Schirlau K, Franken-Kunkel P, Poremba C, Snyderman C, Klotz LO, Ruzicka T, Bier H, Zlotnik A, Whiteside TL, Homey B, Hoffmann TK
International journal of cancer 2006 May 1;118(9):2147-57
International journal of cancer 2006 May 1;118(9):2147-57
Epithelial inflammation is associated with CCL28 production and the recruitment of regulatory T cells expressing CCR10.
Eksteen B, Miles A, Curbishley SM, Tselepis C, Grant AJ, Walker LS, Adams DH
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):593-603
Journal of immunology (Baltimore, Md. : 1950) 2006 Jul 1;177(1):593-603
Distinct chemokine triggers and in vivo migratory paths of fluorescein dye-labeled T Lymphocytes in acutely simian immunodeficiency virus SIVmac251-infected and uninfected macaques.
Clay CC, Rodrigues DS, Harvey DJ, Leutenegger CM, Esser U
Journal of virology 2005 Nov;79(21):13759-68
Journal of virology 2005 Nov;79(21):13759-68
Chemokine networks and in vivo T-lymphocyte trafficking in nonhuman primates.
Clay CC, Rodrigues DS, Brignolo LL, Spinner A, Tarara RP, Plopper CG, Leutenegger CM, Esser U
Journal of immunological methods 2004 Oct;293(1-2):23-42
Journal of immunological methods 2004 Oct;293(1-2):23-42
Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge.
Liu LY, Jarjour NN, Busse WW, Kelly EA
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
The Journal of allergy and clinical immunology 2003 Sep;112(3):556-62
Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS.
Giunti D, Borsellino G, Benelli R, Marchese M, Capello E, Valle MT, Pedemonte E, Noonan D, Albini A, Bernardi G, Mancardi GL, Battistini L, Uccelli A
Journal of leukocyte biology 2003 May;73(5):584-90
Journal of leukocyte biology 2003 May;73(5):584-90
No comments: Submit comment
Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CXCR3 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR3 PE-conjugated Monoclonal Antibody (Catalog # FAB160P) and Mouse Anti-Human CD3 epsilon Alexa Fluor® 700-conjugated Monoclonal Antibody (Catalog # FAB100N). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.