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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 353701 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#353701, RRID:AB_10983069
- Product name
- Purified anti-human CD183 (CXCR3)
- Antibody type
- Monoclonal
- Antigen
- Human CXCR3 transfectants
- Description
- Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T lymphocytes (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed human liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 25 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral lymphocytes were stained with purified anti-human CXCR3 (clone G025H7) (filled histogram) or mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG FITC.
- Conjugate
- Unconjugated
