353704

antibody from BioLegend
Targeting: CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR
Provider product page for 353704

Antibody data

Product number
353704 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#353704, RRID:AB_10983066
Product name
FITC anti-human CD183 (CXCR3)
Antibody type
Monoclonal
Antigen
Human CXCR3 transfectants
Description
Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T lymphocytes (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed human liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CXCR3 protein structure - 353704 shown in red.