353718

antibody from BioLegend
Targeting: CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR
Provider product page for 353718
Flow cytometry
Blocking/Neutralizing

Antibody data

Product number
353718 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#353718, RRID:AB_11150594
Product name
LEAF™ Purified anti-human CD183 (CXCR3) [G025H7]
Antibody type
Monoclonal
Antigen
Human CXCR3 transfectants
Description
Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T lymphocytes (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed human liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
500 µg
Concentration
1 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
CXCR3 protein structure - 353718 shown in red.