Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 353718 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#353718, RRID:AB_11150594
- Product name
- LEAF™ Purified anti-human CD183 (CXCR3) [G025H7]
- Antibody type
- Monoclonal
- Antigen
- Human CXCR3 transfectants
- Description
- Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T lymphocytes (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed human liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 500 µg
- Concentration
- 1 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C. This LEAF™ solution contains no preservative; handle under aseptic conditions.
No comments: Submit comment
Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Anti-human CXCR3 (G025H7) blocks the chemotaxis of Baf3-hCXCR3 transfectants.
- Conjugate
- Unconjugated