Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 334903 - Provider product page
- Provider
- BioLegend
- Product name
- Alexa Fluor® 647 anti-human CD183 (CXCR3) [TG1/CXCR3]
- Antibody type
- Monoclonal
- Antigen
- CXCR3-transfected cells
- Description
- Human CXCR3 is a chemokine receptor that binds CXCL9, CXCL10 and CXCL11 (1, 2). CXCR3 is highly expressed by T lymphocytes (Th1) natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells (3). CXCR3 ligands require IFN-γ for their expression and are localized to sites of inflammation; therefore, CXCR3 is important for effector lymphocyte recruitment into inflamed tissue such as chronically inflamed human liver (4), Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases (5, 6).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 25 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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