334903

antibody from BioLegend
Targeting: CXCR3 CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR
Provider product page for 334903
Flow cytometry

Antibody data

Product number
334903 - Provider product page
Provider
BioLegend
Product name
Alexa Fluor® 647 anti-human CD183 (CXCR3) [TG1/CXCR3]
Antibody type
Monoclonal
Antigen
CXCR3-transfected cells
Description
Human CXCR3 is a chemokine receptor that binds CXCL9, CXCL10 and CXCL11 (1, 2). CXCR3 is highly expressed by T lymphocytes (Th1) natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells (3). CXCR3 ligands require IFN-γ for their expression and are localized to sites of inflammation; therefore, CXCR3 is important for effector lymphocyte recruitment into inflamed tissue such as chronically inflamed human liver (4), Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases (5, 6).
Reactivity
Human
Host
Mouse
Conjugate
Red dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
CXCR3 protein structure - 334903 shown in red.