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Learn23449-1-AP
antibody from Proteintech Group
Targeting: UBQLN2
Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 23449-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- UBQLN2 antibody
- Antibody type
- Polyclonal
- Description
- UBQLN2 antibody (Cat. #23449-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Short disordered termini and proline-rich domain are major regulators of UBQLN1/2/4 phase separation.
The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence.
Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4.
Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies.
Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.
Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
Dao TP, Rajendran A, Galagedera SKK, Haws W, Castañeda CA
Biophysical journal 2024 Jun 4;123(11):1449-1457
Biophysical journal 2024 Jun 4;123(11):1449-1457
The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence.
McDowell I, Ayoubi R, Fotouhi M, Southern K, McPherson PS, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF Consortium
F1000Research 2023;12:355
F1000Research 2023;12:355
Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4.
Dao TP, Rajendran A, Galagedera SKK, Haws W, Castañeda CA
bioRxiv : the preprint server for biology 2023 Sep 29;
bioRxiv : the preprint server for biology 2023 Sep 29;
Tamoxifen improves muscle structure and function of Bin1- and Dnm2-related centronuclear myopathies.
Gineste C, Simon A, Braun M, Reiss D, Laporte J
Brain : a journal of neurology 2023 Jul 3;146(7):3029-3048
Brain : a journal of neurology 2023 Jul 3;146(7):3029-3048
Serpin neuropathology in the P497S UBQLN2 mouse model of ALS/FTD.
Higgins NR, Greenslade JE, Wu JJ, Miranda E, Galliciotti G, Monteiro MJ
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12948
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12948
Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.
Dubos A, Castells-Nobau A, Meziane H, Oortveld MA, Houbaert X, Iacono G, Martin C, Mittelhaeuser C, Lalanne V, Kramer JM, Bhukel A, Quentin C, Slabbert J, Verstreken P, Sigrist SJ, Messaddeq N, Birling MC, Selloum M, Stunnenberg HG, Humeau Y, Schenck A, Herault Y
Human molecular genetics 2015 Dec 1;24(23):6736-55
Human molecular genetics 2015 Dec 1;24(23):6736-55
Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C
Journal of neurochemistry 2014 Apr;129(1):99-106
Journal of neurochemistry 2014 Apr;129(1):99-106
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- rat brain tissue were subjected to SDS PAGE followed by western blot with 23449-1-AP(UBQLN2 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The UBQLN2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human UBQLN2. This antibody recognizes human, rat antigen. The UBQLN2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
