HPA004003

antibody from Atlas Antibodies

Targeting: EZHIP CATACOMB, CXorf67

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA004003

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA004003, RRID:AB_2667113

Product name

Anti-CXorf67

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human CXorf67, Gene description: chromosome X open reading frame 67, Validated applications: ICC, WB, IHC, Uniprot ID: Q86X51, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology

Gödicke S, Kresbach C, Ehlert M, Obrecht D, Altendorf L, Hack K, von Hoff K, Carén H, Melcher V, Kerl K, Englinger B, Filbin M, Pajtler K, Gojo J, Pietsch T, Rutkowski S, Schüller U
Acta Neuropathologica 2024;147(1)

---

Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes

Ajuyah P, Mayoh C, Lau L, Barahona P, Wong M, Chambers H, Valdes-Mora F, Senapati A, Gifford A, D’Arcy C, Hansford J, Manoharan N, Nicholls W, Williams M, Wood P, Cowley M, Tyrrell V, Haber M, Ekert P, Ziegler D, Khuong-Quang D
Scientific Reports 2023;13(1)

---

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

Whitehouse J, Hii H, Mayoh C, Wong M, Ajuyah P, Barahona P, Cui L, Dholaria H, White C, Buntine M, Byrne J, Rodrigues da Silva K, Howlett M, Girard E, Tsoli M, Ziegler D, Dyke J, Lee S, Ekert P, Cowley M, Gottardo N, Endersby R
Frontiers in Oncology 2023;13

---

CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism

Piunti A, Smith E, Morgan M, Ugarenko M, Khaltyan N, Helmin K, Ryan C, Murray D, Rickels R, Yilmaz B, Rendleman E, Savas J, Singer B, Bulun S, Shilatifard A
Science Advances 2019;5(7)

---

PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism

Jain S, Do T, Lund P, Rashoff A, Diehl K, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir T, Garcia B, Jabado N, Lewis P
Nature Communications 2019;10(1)