Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 13861-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13861-1-AP, RRID:AB_2074010
- Product name
- CCPG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CCPG1 antibody (Cat. #13861-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells.
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress.
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression.
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.
Piperine alleviates acute pancreatitis: A possible role for FAM134B and CCPG1 dependent ER-phagy.
Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins.
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.
Li JY, Tian T, Han B, Yang T, Guo YX, Wu JY, Chen YS, Yang Q, Xie RJ
World journal of gastroenterology 2023 Sep 14;29(34):5038-5053
World journal of gastroenterology 2023 Sep 14;29(34):5038-5053
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress.
Pham TNM, Perumal N, Manicam C, Basoglu M, Eimer S, Fuhrmann DC, Pietrzik CU, Clement AM, Körschgen H, Schepers J, Behl C
Redox biology 2023 Nov;67:102943
Redox biology 2023 Nov;67:102943
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression.
Yao M, Pu PM, Li ZY, Zhu K, Zhou LY, Sun YL, Dai YX, Cui XJ, Wang YJ
Journal of pineal research 2023 May;74(4):e12859
Journal of pineal research 2023 May;74(4):e12859
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
Li H, Jing Y, Qu X, Yang J, Pan P, Liu X, Gao H, Pei X, Zhang C, Yang Y
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
Hayashi Y, Takatori S, Warsame WY, Tomita T, Fujisawa T, Ichijo H
The EMBO journal 2023 Dec 1;42(23):e114272
The EMBO journal 2023 Dec 1;42(23):e114272
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.
Ishii S, Chino H, Ode KL, Kurikawa Y, Ueda HR, Matsuura A, Mizushima N, Itakura E
Molecular biology of the cell 2023 Apr 1;34(4):ar29
Molecular biology of the cell 2023 Apr 1;34(4):ar29
Piperine alleviates acute pancreatitis: A possible role for FAM134B and CCPG1 dependent ER-phagy.
Huang W, Zhang J, Jin W, Yang J, Yu G, Shi H, Shi K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154361
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154361
Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
Kennedy A, Ren HY, Madden VJ, Cyr DM
Molecular biology of the cell 2022 Aug 1;33(9):ar84
Molecular biology of the cell 2022 Aug 1;33(9):ar84
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Zielke S, Kardo S, Zein L, Mari M, Covarrubias-Pinto A, Kinzler MN, Meyer N, Stolz A, Fulda S, Reggiori F, Kögel D, van Wijk S
Autophagy 2021 Sep;17(9):2432-2448
Autophagy 2021 Sep;17(9):2432-2448
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins.
Herrera-Cruz MS, Yap MC, Tahbaz N, Phillips K, Thomas L, Thomas G, Simmen T
Biology direct 2021 Nov 7;16(1):22
Biology direct 2021 Nov 7;16(1):22
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Zellner S, Schifferer M, Behrends C
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Chino H, Hatta T, Natsume T, Mizushima N
Molecular cell 2019 Jun 6;74(5):909-921.e6
Molecular cell 2019 Jun 6;74(5):909-921.e6
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW
Molecular cell 2019 Jun 6;74(5):891-908.e10
Molecular cell 2019 Jun 6;74(5):891-908.e10
Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
Cunningham CN, Williams JM, Knupp J, Arunagiri A, Arvan P, Tsai B
Molecular cell 2019 Aug 8;75(3):442-456.e4
Molecular cell 2019 Aug 8;75(3):442-456.e4
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.
Smith MD, Harley ME, Kemp AJ, Wills J, Lee M, Arends M, von Kriegsheim A, Behrends C, Wilkinson S
Developmental cell 2018 Jan 22;44(2):217-232.e11
Developmental cell 2018 Jan 22;44(2):217-232.e11
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 13861-1-AP(CCPG1 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CCPG1 (IP:13861-1-AP, 4ug; Detection:13861-1-AP 1:500) with mouse brain tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 13861-1-AP(CCPG1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCPG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CCPG1. This antibody recognizes human,mouse,rat antigen. The CCPG1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.