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- Antigen structure
- References [27]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 13861-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13861-1-AP, RRID:AB_2074010
- Product name
- CCPG1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CCPG1 antibody (Cat. #13861-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CCPG1-mediated reticulophagy promotes tumorigenesis and cisplatin resistance in bladder cancer.
Membralin Assembles a MAN1B1-VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation.
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Recovery of FAM134A-mediated ER-phagy through BRD4 inhibition alleviates ethanol-induced neurodegeneration.
Mesenchymal stem cells enhance selective ER-phagy to promote α-synuclein clearance in Parkinson's disease.
Membralin Selects Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation.
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity.
Methods for Monitoring ER-Phagy.
ER-phagy restrains inflammatory responses through its receptor UBAC2.
AMFR-mediated Flavivirus NS2A ubiquitination subverts ER-phagy to augment viral pathogenicity.
Oncogenic functions and therapeutic potentials of targeted inhibition of SMARCAL1 in small cell lung cancer.
Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo.
Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells.
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress.
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression.
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.
Piperine alleviates acute pancreatitis: A possible role for FAM134B and CCPG1 dependent ER-phagy.
Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins.
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.
Dong Y, Tian S, Peng X, Wang P, Qian X, Xie C, Tu R, Wang X, Cui Y
Autophagy 2026 Mar;22(3):586-602
Autophagy 2026 Mar;22(3):586-602
Membralin Assembles a MAN1B1-VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation.
Zhang J, Lu X, Li S, Wang T, Ahmad I, Zheng YH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(9):e19256
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(9):e19256
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Dong Z, Chen Q, Li F, Xie W, Ma X, Ge S, Sun M, Zhao X, Zhang Z, Zhang W, Wei D, Huang S
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Recovery of FAM134A-mediated ER-phagy through BRD4 inhibition alleviates ethanol-induced neurodegeneration.
Lim JR, Chae CW, Yoon JH, Cho JH, Park JY, Han SJ, Chang HS, Kim SY, Kim HJ, Jung YH, Han HJ
International journal of biological sciences 2025;21(12):5167-5184
International journal of biological sciences 2025;21(12):5167-5184
Mesenchymal stem cells enhance selective ER-phagy to promote α-synuclein clearance in Parkinson's disease.
Lee JE, Oh KW, Shin JY, Kim YJ, Lee SJ, Lee PH
Stem cells translational medicine 2025 May 31;14(6)
Stem cells translational medicine 2025 May 31;14(6)
Membralin Selects Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation.
Zheng YH, Zhang J, Lu X, Li S, Wang T, Ahmad I
Research square 2025 Jun 23;
Research square 2025 Jun 23;
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity.
Jin S, Yan M, Liu Y, Zhang S, Song H, Cao C, Li Y, Sun G, Ye L, Chen J, Han W, Li L, Chang Q
Autophagy 2025 Dec;21(12):2614-2632
Autophagy 2025 Dec;21(12):2614-2632
Methods for Monitoring ER-Phagy.
Di Monaco M, Peteri M, Liang JR
Methods in molecular biology (Clifton, N.J.) 2024;2845:109-126
Methods in molecular biology (Clifton, N.J.) 2024;2845:109-126
ER-phagy restrains inflammatory responses through its receptor UBAC2.
He X, He H, Hou Z, Wang Z, Shi Q, Zhou T, Wu Y, Qin Y, Wang J, Cai Z, Cui J, Jin S
The EMBO journal 2024 Nov;43(21):5057-5084
The EMBO journal 2024 Nov;43(21):5057-5084
AMFR-mediated Flavivirus NS2A ubiquitination subverts ER-phagy to augment viral pathogenicity.
Zhang L, Wang H, Han C, Dong Q, Yan J, Guo W, Shan C, Zhao W, Chen P, Huang R, Wu Y, Chen Y, Qin Y, Chen M
Nature communications 2024 Nov 6;15(1):9578
Nature communications 2024 Nov 6;15(1):9578
Oncogenic functions and therapeutic potentials of targeted inhibition of SMARCAL1 in small cell lung cancer.
Sun BB, Wang GZ, Han SC, Yang FY, Guo H, Liu J, Liu YT, Zhou GB
Cancer letters 2024 Jun 28;592:216929
Cancer letters 2024 Jun 28;592:216929
Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo.
Iavarone F, Zaninello M, Perrone M, Monaco M, Barth E, Gaedke F, Pizzo MT, Di Lorenzo G, Desiderio V, Sommella E, Merciai F, Salviati E, Campiglia P, Luongo L, De Leonibus E, Rugarli E, Settembre C
EMBO reports 2024 Aug;25(8):3651-3677
EMBO reports 2024 Aug;25(8):3651-3677
Suberoylanilide hydroxamic acid upregulates reticulophagy receptor expression and promotes cell death in hepatocellular carcinoma cells.
Li JY, Tian T, Han B, Yang T, Guo YX, Wu JY, Chen YS, Yang Q, Xie RJ
World journal of gastroenterology 2023 Sep 14;29(34):5038-5053
World journal of gastroenterology 2023 Sep 14;29(34):5038-5053
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress.
Pham TNM, Perumal N, Manicam C, Basoglu M, Eimer S, Fuhrmann DC, Pietrzik CU, Clement AM, Körschgen H, Schepers J, Behl C
Redox biology 2023 Nov;67:102943
Redox biology 2023 Nov;67:102943
Melatonin restores endoplasmic reticulum homeostasis to protect injured neurons in a rat model of chronic cervical cord compression.
Yao M, Pu PM, Li ZY, Zhu K, Zhou LY, Sun YL, Dai YX, Cui XJ, Wang YJ
Journal of pineal research 2023 May;74(4):e12859
Journal of pineal research 2023 May;74(4):e12859
The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis.
Li H, Jing Y, Qu X, Yang J, Pan P, Liu X, Gao H, Pei X, Zhang C, Yang Y
International journal of molecular sciences 2023 Feb 1;24(3)
International journal of molecular sciences 2023 Feb 1;24(3)
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
Hayashi Y, Takatori S, Warsame WY, Tomita T, Fujisawa T, Ichijo H
The EMBO journal 2023 Dec 1;42(23):e114272
The EMBO journal 2023 Dec 1;42(23):e114272
CCPG1 recognizes endoplasmic reticulum luminal proteins for selective ER-phagy.
Ishii S, Chino H, Ode KL, Kurikawa Y, Ueda HR, Matsuura A, Mizushima N, Itakura E
Molecular biology of the cell 2023 Apr 1;34(4):ar29
Molecular biology of the cell 2023 Apr 1;34(4):ar29
Piperine alleviates acute pancreatitis: A possible role for FAM134B and CCPG1 dependent ER-phagy.
Huang W, Zhang J, Jin W, Yang J, Yu G, Shi H, Shi K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154361
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Oct;105:154361
Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin.
Kennedy A, Ren HY, Madden VJ, Cyr DM
Molecular biology of the cell 2022 Aug 1;33(9):ar84
Molecular biology of the cell 2022 Aug 1;33(9):ar84
ATF4 links ER stress with reticulophagy in glioblastoma cells.
Zielke S, Kardo S, Zein L, Mari M, Covarrubias-Pinto A, Kinzler MN, Meyer N, Stolz A, Fulda S, Reggiori F, Kögel D, van Wijk S
Autophagy 2021 Sep;17(9):2432-2448
Autophagy 2021 Sep;17(9):2432-2448
Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins.
Herrera-Cruz MS, Yap MC, Tahbaz N, Phillips K, Thomas L, Thomas G, Simmen T
Biology direct 2021 Nov 7;16(1):22
Biology direct 2021 Nov 7;16(1):22
Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.
Zellner S, Schifferer M, Behrends C
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Molecular cell 2021 Mar 18;81(6):1337-1354.e8
Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Chino H, Hatta T, Natsume T, Mizushima N
Molecular cell 2019 Jun 6;74(5):909-921.e6
Molecular cell 2019 Jun 6;74(5):909-921.e6
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
An H, Ordureau A, Paulo JA, Shoemaker CJ, Denic V, Harper JW
Molecular cell 2019 Jun 6;74(5):891-908.e10
Molecular cell 2019 Jun 6;74(5):891-908.e10
Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
Cunningham CN, Williams JM, Knupp J, Arunagiri A, Arvan P, Tsai B
Molecular cell 2019 Aug 8;75(3):442-456.e4
Molecular cell 2019 Aug 8;75(3):442-456.e4
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.
Smith MD, Harley ME, Kemp AJ, Wills J, Lee M, Arends M, von Kriegsheim A, Behrends C, Wilkinson S
Developmental cell 2018 Jan 22;44(2):217-232.e11
Developmental cell 2018 Jan 22;44(2):217-232.e11
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 13861-1-AP(CCPG1 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-CCPG1 (IP:13861-1-AP, 4ug; Detection:13861-1-AP 1:500) with mouse brain tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 13861-1-AP(CCPG1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CCPG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CCPG1. This antibody recognizes human,mouse,rat antigen. The CCPG1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
