abx027471

antibody from Abbexa

Targeting: ZFX ZNF926

Western blot (Recommended by provider)

Antibody Data

Product number

abx027471

Provider

Abbexa

Product name

Zinc Finger Protein, X-Linked (ZFX) Antibody

Antibody type

Polyclonal

Description

This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Concentration

0.44 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.