Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 11528-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11528-1-AP, RRID:AB_2194708
- Product name
- SRP14 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SRP14 antibody (Cat. #11528-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification.
Identification of a minimal Alu domain required for retrotransposition.
The nucleolar phase of signal recognition particle assembly.
Expression of signal recognition particle 14 in hepatocellular carcinoma and its relationship with disease progression and patient survival.
Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival.
Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival.
Nuclear SRP9/SRP14 heterodimer transcriptionally regulates 7SL and BC200 RNA expression.
Alu RNA fold links splicing with signal recognition particle proteins.
The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells.
Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover.
Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.
Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.
Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.
Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs.
Liu B, Wu T, Miao BA, Ji F, Liu S, Wang P, Zhao Y, Zhong Y, Sundaram A, Zeng TB, Majcherska-Agrawal M, Keenan RJ, Pan T, He C
Cell 2025 Jan 23;188(2):465-483.e22
Cell 2025 Jan 23;188(2):465-483.e22
Identification of a minimal Alu domain required for retrotransposition.
Moldovan JB, Yin J, Moran JV
bioRxiv : the preprint server for biology 2024 Dec 16;
bioRxiv : the preprint server for biology 2024 Dec 16;
The nucleolar phase of signal recognition particle assembly.
Issa A, Schlotter F, Flayac J, Chen J, Wacheul L, Philippe M, Sardini L, Mostefa L, Vandermoere F, Bertrand E, Verheggen C, Lafontaine DL, Massenet S
Life science alliance 2024 Aug;7(8)
Life science alliance 2024 Aug;7(8)
Expression of signal recognition particle 14 in hepatocellular carcinoma and its relationship with disease progression and patient survival.
Tian H, Tang D, Ma M, Fu X
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2024 Aug 25;53(4):460-471
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 2024 Aug 25;53(4):460-471
Tetracycline-dependent inhibition of mitoribosome protein elongation in mitochondrial disease mutant cells suppresses IRE1α to promote cell survival.
Ronayne CT, Bennett CF, Perry EA, Kantorovich N, Puigserver P
bioRxiv : the preprint server for biology 2023 Mar 21;
bioRxiv : the preprint server for biology 2023 Mar 21;
Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival.
Ronayne CT, Jackson TD, Bennett CF, Perry EA, Kantorovic N, Puigserver P
EMBO reports 2023 Dec 6;24(12):e57228
EMBO reports 2023 Dec 6;24(12):e57228
Nuclear SRP9/SRP14 heterodimer transcriptionally regulates 7SL and BC200 RNA expression.
Gussakovsky D, Booy EP, Brown MJF, McKenna SA
RNA (New York, N.Y.) 2023 Aug;29(8):1185-1200
RNA (New York, N.Y.) 2023 Aug;29(8):1185-1200
Alu RNA fold links splicing with signal recognition particle proteins.
Borovská I, Vořechovský I, Královičová J
Nucleic acids research 2023 Aug 25;51(15):8199-8216
Nucleic acids research 2023 Aug 25;51(15):8199-8216
The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells.
Booy EP, Gussakovsky D, Choi T, McKenna SA
The Journal of biological chemistry 2021 Jan-Jun;296:100036
The Journal of biological chemistry 2021 Jan-Jun;296:100036
Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover.
Li D, Chen J, Ai Y, Gu X, Li L, Che D, Jiang Z, Li L, Chen S, Huang H, Wang J, Cai T, Cao Y, Qi X, Wang X
Molecular cell 2019 Sep 19;75(6):1103-1116.e9
Molecular cell 2019 Sep 19;75(6):1103-1116.e9
Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.
Booy EP, McRae EK, Ezzati P, Choi T, Gussakovsky D, McKenna SA
Nucleic acids research 2018 Nov 30;46(21):11575-11591
Nucleic acids research 2018 Nov 30;46(21):11575-11591
The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.
Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P
eLife 2018 Dec 24;7
eLife 2018 Dec 24;7
Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer.
Nabet BY, Qiu Y, Shabason JE, Wu TJ, Yoon T, Kim BC, Benci JL, DeMichele AM, Tchou J, Marcotrigiano J, Minn AJ
Cell 2017 Jul 13;170(2):352-366.e13
Cell 2017 Jul 13;170(2):352-366.e13
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.
Fittschen M, Lastres-Becker I, Halbach MV, Damrath E, Gispert S, Azizov M, Walter M, Müller S, Auburger G
Neurogenetics 2015 Jul;16(3):181-92
Neurogenetics 2015 Jul;16(3):181-92
Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.
Piazzon N, Schlotter F, Lefebvre S, Dodré M, Méreau A, Soret J, Besse A, Barkats M, Bordonné R, Branlant C, Massenet S
Nucleic acids research 2013 Jan;41(2):1255-72
Nucleic acids research 2013 Jan;41(2):1255-72
Human intron-encoded Alu RNAs are processed and packaged into Wdr79-associated nucleoplasmic box H/ACA RNPs.
Jády BE, Ketele A, Kiss T
Genes & development 2012 Sep 1;26(17):1897-910
Genes & development 2012 Sep 1;26(17):1897-910
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 11528-1-AP(SRP14 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using SRP14 antibody 11528-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line