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- References [13]
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- Product number
- 12199-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12199-1-AP, RRID:AB_2212771
- Product name
- USP25 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP25 antibody (Cat. #12199-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP25 aggravates liver cancer development and impairs chemosensitivity by limiting LATS1 activation.
The role and regulatory mechanism of USP25 in pancreatic microcirculatory disturbance in severe acute pancreatitis.
The long noncoding RNA SNHG12 defines KEAP1 stability and ferroptosis susceptibility by targeting E3 ligase TRIM25.
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
USP28 promotes PARP inhibitor resistance by enhancing SOX9-mediated DNA damage repair in ovarian cancer.
USP25 Elevates SHLD2-Mediated DNA Double-Strand Break Repair and Regulates Chemoresponse in Cancer.
USP25 attenuates anti-GBM nephritis in mice by negative feedback regulation of Th17 cell differentiation.
The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage.
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.
Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis.
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
An Interaction Landscape of Ubiquitin Signaling.
Li L, Wang X, Yang Y, Zhou Y, Jiang Z, Zhai L, Zhao X, Qiang H, Luo J, Ji Y, Yao J, Zhang T, Wang Y, Li K, Chen L, Chen Y, Yuan J, Li Y
EMBO reports 2026 May;27(9):2406-2433
EMBO reports 2026 May;27(9):2406-2433
The role and regulatory mechanism of USP25 in pancreatic microcirculatory disturbance in severe acute pancreatitis.
Zhang Q, Zhang X, Shan F
Scientific reports 2026 Mar 2;16(1)
Scientific reports 2026 Mar 2;16(1)
The long noncoding RNA SNHG12 defines KEAP1 stability and ferroptosis susceptibility by targeting E3 ligase TRIM25.
Guo Y, Zhu S, Wu W, Cai Y, Sehgal SA, Huang F, Wu H
The Journal of biological chemistry 2025 Oct;301(10):110689
The Journal of biological chemistry 2025 Oct;301(10):110689
Targeting Irgm1 to combat osteoporosis: suppressing ROS and restoring bone remodeling.
Cui Z, Gu G, Chen F, Li J, Du X, Chen S, Zhang H, Li C, Shao J, Xi J, Du Y, Zhao Q, Xi Y
Cell death & disease 2025 Aug 27;16(1):651
Cell death & disease 2025 Aug 27;16(1):651
USP28 promotes PARP inhibitor resistance by enhancing SOX9-mediated DNA damage repair in ovarian cancer.
Han F, Qi G, Li R, Peng J, Yan S, Yuan C, Kong B, Ma H
Cell death & disease 2025 Apr 16;16(1):305
Cell death & disease 2025 Apr 16;16(1):305
USP25 Elevates SHLD2-Mediated DNA Double-Strand Break Repair and Regulates Chemoresponse in Cancer.
Li Y, Li L, Wang X, Zhao F, Yang Y, Zhou Y, Zhang J, Wang L, Jiang Z, Zhang Y, Chen Y, Wu C, Li K, Zhang T, Wang P, Mao Z, Zhu W, Xu X, Liang S, Lou Z, Yuan J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2403485
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2403485
USP25 attenuates anti-GBM nephritis in mice by negative feedback regulation of Th17 cell differentiation.
Xu R, Huang F, Liu Q, Lv Y, Hu L, Zhang Q
Renal failure 2024 Dec;46(1):2338932
Renal failure 2024 Dec;46(1):2338932
The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage.
Jin C, Einig E, Xu W, Kollampally RB, Schlosser A, Flentje M, Popov N
Nucleic acids research 2024 Apr 12;52(6):3011-3030
Nucleic acids research 2024 Apr 12;52(6):3011-3030
Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease.
Ren Y, Zhu X, Fu K, Zhang H, Zhao W, Lin Y, Fang Q, Wang J, Chen Y, Guo D
Biochemical pharmacology 2023 Jan;207:115355
Biochemical pharmacology 2023 Jan;207:115355
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.
Black HL, Livingstone R, Mastick CC, Al Tobi M, Taylor H, Geiser A, Stirrat L, Kioumourtzoglou D, Petrie JR, Boyle JG, Bryant NJ, Gould GW
Journal of cell science 2022 Dec 1;135(1)
Journal of cell science 2022 Dec 1;135(1)
Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis.
Jiang S, Wang X, He Y, Huang H, Cao B, Zhang Z, Liu J, Wang Q, Huang Z, Mao X
Cell death & disease 2021 May 7;12(5):456
Cell death & disease 2021 May 7;12(5):456
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Ding J, Cheng Y, Zhang Y, Liao S, Yin T, Yang J
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Journal of cellular physiology 2019 Nov;234(11):19951-19963
An Interaction Landscape of Ubiquitin Signaling.
Zhang X, Smits AH, van Tilburg GB, Jansen PW, Makowski MM, Ovaa H, Vermeulen M
Molecular cell 2017 Mar 2;65(5):941-955.e8
Molecular cell 2017 Mar 2;65(5):941-955.e8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP25 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human USP25. This antibody recognizes human, mouse, rat antigen. The USP25 antibody has been validated for the following applications: ELISA, WB analysis.
