- PAB4214 - Abnova Corporation USP25 antibody

Submitted references Complete sequencing and characterization of 21,243 full-length human cDNAs.

Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S
Nature genetics 2004 Jan;36(1):40-5

Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment.

Groet J, Ives JH, Jones TA, Danton M, Flomen RH, Sheer D, Hrascan R, Pavelic K, Nizetic D
Genes, chromosomes & cancer 2000 Feb;27(2):153-61

USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2.

Valero R, Marfany G, González-Angulo O, González-González G, Puelles L, Gonzàlez-Duarte R
Genomics 1999 Dec 15;62(3):395-405

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Supportive validation

Submitted by: Abnova Corporation (provider)
Main image
Experimental details: The USP25 polyclonal antibody (Cat # PAB4214) is used in Western blot to detect USP25-transfected HeLa cell lysates . Transfection data is kindly provided by Dr . B . Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland) .

Supportive validation

Submitted by: Abnova Corporation (provider)
Main image
Experimental details: The USP25 polyclonal antibody (Cat # PAB4214) is used in Western blot to detect USP25 in rat testis tissue lysate . Transfection data is kindly provided by Dr . B . Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland) .

Supportive validation

Submitted by: Abnova Corporation (provider)
Main image
Experimental details: Formalin-fixed and paraffin-embedded human cancer tissue reacted with USP25 polyclonal antibody (Cat # PAB4214) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
Validation comment: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

PAB4214

Antibody data