55313-1-AP

antibody from Proteintech Group

Targeting: MT-ATP6 ATP6, ATPase-6, MTATP6, RP, Su6m

Provider product page for 55313-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [46]
Comments [0]
Validations [0]

Submit

Product number: 55313-1-AP - Provider product page
Provider: Proteintech Group
Product name: ATP6 antibody
Antibody type: Polyclonal
Description: ATP6 antibody (Cat. #55313-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MT-ATP6 protein structure - 55313-1-AP shown in red.

Submitted references Dual targeting of wild-type p53 and gut microbiota by Magnolol represses key metabolic process and kills CRC cells.

Ji H, Qiao O, Zhang Y, Wang W, Han X, Zhang X, Liu C, Gao W
Phytotherapy research : PTR 2024 Oct;38(10):4982-4998

Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.

Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9

Transketolase promotes MAFLD by limiting inosine-induced mitochondrial activity.

Tong L, Chen Z, Li Y, Wang X, Yang C, Li Y, Zhu Y, Lu Y, Liu Q, Xu N, Shao S, Wu L, Zhang P, Wu G, Wu X, Chen X, Fang J, Jia R, Xu T, Li B, Zheng L, Liu J, Tong X
Cell metabolism 2024 May 7;36(5):1013-1029.e5

Single-nucleoid architecture reveals heterogeneous packaging of mitochondrial DNA.

Isaac RS, Tullius TW, Hansen KG, Dubocanin D, Couvillion M, Stergachis AB, Churchman LS
Nature structural & molecular biology 2024 Mar;31(3):568-577

Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH.

Weiss M, Hettrich S, Hofmann T, Hachim S, Günther S, Braun T, Boettger T
Nucleic acids research 2024 Jun 24;52(11):6629-6646

Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.

Kim JY, Atanassov I, Dethloff F, Kroczek L, Langer T
Life science alliance 2023 Sep;6(9)

FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes.

Qiu J, Yue F, Zhu P, Chen J, Xu F, Zhang L, Kim KH, Snyder MM, Luo N, Xu HW, Huang F, Tao WA, Kuang S
Nature communications 2023 Oct 10;14(1):6344

Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression.

Kramer NJ, Prakash G, Isaac RS, Choquet K, Soto I, Petrova B, Merens HE, Kanarek N, Churchman LS
Nature cell biology 2023 Nov;25(11):1575-1589

Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway.

Zhang J, Simpson CM, Berner J, Chong HB, Fang J, Ordulu Z, Weiss-Sadan T, Possemato AP, Harry S, Takahashi M, Yang TY, Richter M, Patel H, Smith AE, Carlin AD, Hubertus de Groot AF, Wolf K, Shi L, Wei TY, Dürr BR, Chen NJ, Vornbäumen T, Wichmann NO, Mahamdeh MS, Pooladanda V, Matoba Y, Kumar S, Kim E, Bouberhan S, Oliva E, Rueda BR, Soberman RJ, Bardeesy N, Liau BB, Lawrence M, Stokes MP, Beausoleil SA, Bar-Peled L
Cell 2023 May 25;186(11):2361-2379.e25

Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m(3)C modification.

Zhang F, Yoon K, Zhang DY, Kim NS, Ming GL, Song H
Cell stem cell 2023 Mar 2;30(3):300-311.e11

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway.

Zhang J, Simpson CM, Berner J, Chong HB, Fang J, Sahin ZO, Weiss-Sadan T, Possemato AP, Harry S, Takahashi M, Yang TY, Richter M, Patel H, Smith AE, Carlin AD, Hubertus de Groot AF, Wolf K, Shi L, Wei TY, Dürr BR, Chen NJ, Vornbäumen T, Wichmann NO, Pooladanda V, Matoba Y, Kumar S, Kim E, Bouberhan S, Olivia E, Rueda B, Bardeesy N, Liau B, Lawrence M, Stokes MP, Beausoleil SA, Bar-Peled L
bioRxiv : the preprint server for biology 2023 Mar 11;

PBDE-47 induces impairment of mitochondrial biogenesis and subsequent neurotoxicity through miR-128-3p/PGC-1α axis.

Tian Z, Li J, Song L, Xie L, Li D, Xia T, Wang A
Toxicological sciences : an official journal of the Society of Toxicology 2023 Jan 31;191(1):123-134

Cultured lymphocytes' mitochondrial genome integrity is not altered by cladribine.

Järvinen E, Suomi F, Stewart JB, Guala D, Valori M, Jansson L, Nieminen J, McWilliams TG, Tienari PJ
Clinical and experimental immunology 2023 Dec 13;214(3):304-313

Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.

Li D, Zhao Q, Xie L, Wang C, Tian Z, Tang H, Xia T, Wang A
The Science of the total environment 2023 Apr 15;869:161738

TMPRSS12 Functions in Meiosis and Spermiogenesis and Is Required for Male Fertility in Mice.

Zhang J, Zhou X, Wan D, Yu L, Chen X, Yan T, Wu Z, Zheng M, Zhu F, Zhu H
Frontiers in cell and developmental biology 2022;10:757042

Nonstop mRNAs generate a ground state of mitochondrial gene expression noise.

Ng KY, Lutfullahoglu Bal G, Richter U, Safronov O, Paulin L, Dunn CD, Paavilainen VO, Richer J, Newman WG, Taylor RW, Battersby BJ
Science advances 2022 Nov 16;8(46):eabq5234

Carbon tetrachloride induced mitochondrial division, respiratory chain damage, abnormal intracellular [H(+)] and apoptosis are due to the activation of 5-HT degradation system in hepatocytes.

Zhang Y, Liang X, Guan J, Jin J, Zhang Y, Xu F, Fu J
Toxicology and applied pharmacology 2022 Mar 15;439:115929

LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.

Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)

MOTS-c increases in skeletal muscle following long-term physical activity and improves acute exercise performance after a single dose.

Hyatt JK
Physiological reports 2022 Jul;10(13):e15377

TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs.

Liang X, He M, Zhu B, Zhu Y, He X, Liu D, Wei Q
Frontiers in cell and developmental biology 2021;9:726549

ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.

Yang Y, Li C, Gu X, Zhen J, Zhu S, Lv T, Wan Q, Liu Y
Frontiers in cell and developmental biology 2021;9:700195

A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.

Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.

Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)

Mtu1 defects are correlated with reduced osteogenic differentiation.

He Q, Zhao Q, Li Q, Pan R, Li X, Chen Y
Cell death & disease 2021 Jan 11;12(1):61

Modulation of OSCP mitigates mitochondrial and synaptic deficits in a mouse model of Alzheimer's pathology.

Gauba E, Sui S, Tian J, Driskill C, Jia K, Yu C, Rughwani T, Wang Q, Kroener S, Guo L, Du H
Neurobiology of aging 2021 Feb;98:63-77

TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.

Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142

Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.

Gu X, Liu Y, Wang N, Zhen J, Zhang B, Hou S, Cui Z, Wan Q, Feng H
Free radical biology & medicine 2021 Feb 20;164:329-340

Tissue-specific expression atlas of murine mitochondrial tRNAs.

He Q, He X, Xiao Y, Zhao Q, Ye Z, Cui L, Chen Y, Guan MX
The Journal of biological chemistry 2021 Aug;297(2):100960

Maternally Inherited Diabetes Mellitus Associated with a Novel m.15897G>A Mutation in Mitochondrial tRNA(Thr) Gene.

Li K, Wu L, Liu J, Lin W, Qi Q, Zhao T
Journal of diabetes research 2020;2020:2057187

SIRT1-dependent mitochondrial biogenesis supports therapeutic effects of resveratrol against neurodevelopment damage by fluoride.

Zhao Q, Tian Z, Zhou G, Niu Q, Chen J, Li P, Dong L, Xia T, Zhang S, Wang A
Theranostics 2020;10(11):4822-4838

Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.

Tian N, Liu Q, Li Y, Tong L, Lu Y, Zhu Y, Zhang P, Chen H, Hu L, Meng J, Feng M, Li M, Zheng L, Li B, Xu T, Wu L, Tong X
Diabetes 2020 Jul;69(7):1355-1367

SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.

Ma Y, Zhu S, Lv T, Gu X, Feng H, Zhen J, Xin W, Wan Q
iScience 2020 Aug 21;23(8):101428

Mitochondrial stress response triggered by defects in protein synthesis quality control.

Richter U, Ng KY, Suomi F, Marttinen P, Turunen T, Jackson C, Suomalainen A, Vihinen H, Jokitalo E, Nyman TA, Isokallio MA, Stewart JB, Mancini C, Brusco A, Seneca S, Lombès A, Taylor RW, Battersby BJ
Life science alliance 2019 Feb;2(1)

A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.

Jia Z, Zhang Y, Li Q, Ye Z, Liu Y, Fu C, Cang X, Wang M, Guan MX
Nucleic acids research 2019 Feb 28;47(4):2056-2074

EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.

Sha Y, Liu W, Huang X, Li Y, Ji Z, Mei L, Lin S, Kong S, Lu J, Kong L, Zhu X, Lu Z, Ding L
Molecular genetics & genomic medicine 2019 Aug;7(8):e807

Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3.

Fu R, Yang P, Li Z, Liu W, Amin S, Li Z
Cell death & disease 2019 Aug 7;10(8):593

Protective effects of β- nicotinamide adenine dinucleotide against motor deficits and dopaminergic neuronal damage in a mouse model of Parkinson's disease.

Shan C, Gong YL, Zhuang QQ, Hou YF, Wang SM, Zhu Q, Huang GR, Tao B, Sun LH, Zhao HY, Li ST, Liu JM
Progress in neuro-psychopharmacology & biological psychiatry 2019 Aug 30;94:109670

The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα.

Iershov A, Nemazanyy I, Alkhoury C, Girard M, Barth E, Cagnard N, Montagner A, Chretien D, Rugarli EI, Guillou H, Pende M, Panasyuk G
Nature communications 2019 Apr 5;10(1):1566

Leber's hereditary optic neuropathy caused by a mutation in mitochondrial tRNA(Thr) in eight Chinese pedigrees.

Zhang J, Ji Y, Liu X, Chen J, Wang B, Zhang M, Guan MX
Mitochondrion 2018 Sep;42:84-91

RNA modification landscape of the human mitochondrial tRNA(Lys) regulates protein synthesis.

Richter U, Evans ME, Clark WC, Marttinen P, Shoubridge EA, Suomalainen A, Wredenberg A, Wedell A, Pan T, Battersby BJ
Nature communications 2018 Sep 27;9(1):3966

Biallelic mutations in mitochondrial tryptophanyl-tRNA synthetase cause Levodopa-responsive infantile-onset Parkinsonism.

Burke EA, Frucht SJ, Thompson K, Wolfe LA, Yokoyama T, Bertoni M, Huang Y, Sincan M, Adams DR, Taylor RW, Gahl WA, Toro C, Malicdan MCV
Clinical genetics 2018 Mar;93(3):712-718

A hypertension-associated mitochondrial DNA mutation introduces an m(1)G37 modification into tRNA(Met), altering its structure and function.

Zhou M, Xue L, Chen Y, Li H, He Q, Wang B, Meng F, Wang M, Guan MX
The Journal of biological chemistry 2018 Jan 26;293(4):1425-1438

Florfenicol-induced Mitochondrial Dysfunction Suppresses Cell Proliferation and Autophagy in Fibroblasts.

Hu D, Cao S, Zhang G, Xiao Y, Liu S, Shang Y
Scientific reports 2017 Oct 19;7(1):13554

Base-Resolution Mapping Reveals Distinct m(1)A Methylome in Nuclear- and Mitochondrial-Encoded Transcripts.

Li X, Xiong X, Zhang M, Wang K, Chen Y, Zhou J, Mao Y, Lv J, Yi D, Chen XW, Wang C, Qian SB, Yi C
Molecular cell 2017 Dec 7;68(5):993-1005.e9

A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNA(Leu(UUR)).

Zhou M, Wang M, Xue L, Lin Z, He Q, Shi W, Chen Y, Jin X, Li H, Jiang P, Guan MX
The Journal of biological chemistry 2017 Aug 25;292(34):13934-13946

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.

Beck SJ, Guo L, Phensy A, Tian J, Wang L, Tandon N, Gauba E, Lu L, Pascual JM, Kroener S, Du H
Nature communications 2016 May 6;7:11483

No comments: Submit comment

No validations: Submit validation data