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- References [10]
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- Product number
- 11179-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11179-1-AP, RRID:AB_2204687
- Product name
- TIMM8A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TIMM8A antibody (Cat. #11179-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TIMM8A-TIMM13 Complex Exerts Oncogenic Functions in Lung Cancer.
SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis.
The oncogenic role of TIMM8A in cancer and the mechanistic insights into the function in breast cancer cells.
CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome.
TIM8 Deficiency in Yeast Induces Endoplasmic Reticulum Stress and Shortens the Chronological Lifespan.
Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium.
Stress response silencing by an E3 ligase mutated in neurodegeneration.
Functional analysis of a novel mutation in the TIMM8A gene that causes deafness-dystonia-optic neuronopathy syndrome.
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.
Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.
Li S, Shi K, Wang Y, Zhang Y
Oncology research 2025;33(9):2435-2449
Oncology research 2025;33(9):2435-2449
SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis.
Dias MM, King MS, Shokry E, Lilla S, Paul N, Thomason P, Zanivan S, Sumpton D, Kunji ERS, MacVicar T
Molecular cell 2025 Nov 6;85(21):4093-4104.e8
Molecular cell 2025 Nov 6;85(21):4093-4104.e8
The oncogenic role of TIMM8A in cancer and the mechanistic insights into the function in breast cancer cells.
Wang W, Liu M, Wu H, Li J, Lv W, Li C, Du C, Feng C, Zhang Y, Cai Y, Jia Y, Hu Y, Qu J, Zhang S, Wu F
Scientific reports 2025 May 26;15(1):18374
Scientific reports 2025 May 26;15(1):18374
CHCHD2 rescues the mitochondrial dysfunction in iPSC-derived neurons from patient with Mohr-Tranebjaerg syndrome.
Huang Y, Chen Z, Deng W, Jiang Y, Pan Y, Yuan Z, Hu H, Wu Y, Hu Y
Cell death & disease 2025 Mar 12;16(1):173
Cell death & disease 2025 Mar 12;16(1):173
TIM8 Deficiency in Yeast Induces Endoplasmic Reticulum Stress and Shortens the Chronological Lifespan.
Tang D, Guan W, Yang X, Li Z, Zhao W, Liu X
Biomolecules 2025 Feb 12;15(2)
Biomolecules 2025 Feb 12;15(2)
Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium.
Zheng J, Yu R, Tang Y, Su S, Wang S, Liao C, Li X, Liao J, Yu D, Ai T, Zhao W, Yau V, Liu C, Wu L, Cao Y
Genes & diseases 2024 Sep;11(5):101194
Genes & diseases 2024 Sep;11(5):101194
Stress response silencing by an E3 ligase mutated in neurodegeneration.
Haakonsen DL, Heider M, Ingersoll AJ, Vodehnal K, Witus SR, Uenaka T, Wernig M, Rapé M
Nature 2024 Feb;626(8000):874-880
Nature 2024 Feb;626(8000):874-880
Functional analysis of a novel mutation in the TIMM8A gene that causes deafness-dystonia-optic neuronopathy syndrome.
Neighbors A, Moss T, Holloway L, Yu SH, Annese F, Skinner S, Saneto R, Steet R
Molecular genetics & genomic medicine 2020 Mar;8(3):e1121
Molecular genetics & genomic medicine 2020 Mar;8(3):e1121
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.
Kang Y, Anderson AJ, Jackson TD, Palmer CS, De Souza DP, Fujihara KM, Stait T, Frazier AE, Clemons NJ, Tull D, Thorburn DR, McConville MJ, Ryan MT, Stroud DA, Stojanovski D
eLife 2019 Nov 4;8
eLife 2019 Nov 4;8
Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.
Sun Y, Li T, Xie C, Xu Y, Zhou K, Rodriguez J, Han W, Wang X, Kroemer G, Modjtahedi N, Blomgren K, Zhu C
Cell death & disease 2017 May 11;8(5):e2781
Cell death & disease 2017 May 11;8(5):e2781
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The TIMM8A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TIMM8A. This antibody recognizes human, mouse, rat antigen. The TIMM8A antibody has been validated for the following applications: ELISA, WB analysis.
