FNab07517

antibody from FineTest Biotech

Targeting: RTEL1 bK3184A7.3, C20orf41, DKFZP434C013, KIAA1088, NHL, RTEL

Western blot

ELISA

Antibody data

Submit

Validation data

Product number: FNab07517 - Provider product page
Provider: FineTest Biotech
Product name: RTEL1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: regulator of telomere elongation he licase 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

RTEL1 protein structure - FNab07517 shown in red.