BS7230
antibody from Bioworld Technology, Inc
Targeting: H3C4
H3/b, H3FB, HIST1H3D
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS7230 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- Histone H3 (Mono Methyl K4) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide conjugated to KLH derived from within residues 1-100 of Human Histone H3, mono methylated at K4.
- Description
- Modulation of chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of DNA wound around eight core histone proteins (two each of H2A, H2B, H3, and H4), is the primary building block of chromatin. The amino-terminal tails of core histones undergo various post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination. These modifications occur in response to various stimuli and have a direct effect on the accessibility of chromatin to transcription factors and, therefore, gene expression. In most species, Histone H3 is primarily acetylated at Lys9, 14, 18, 23, 27, and 56.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of extracts of HeLa cell line and H3 protein expressed in E.coli., using Histone H3 (Mono-Methyl K4) antibody.