BS7868

SERPINA6 antibody from Bioworld Technology, Inc
CBG
Western blot
Supportive data in Antibodypedia
Immunocytochemistry
Data presented on provider website
Immunohistochemistry
Data presented on provider website

Antibody data

Product number
BS7868
Provider
Bioworld Technology, Inc
Product name
SERPINA6 polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS7868
Antibody type
Polyclonal
Antigen
Recombinant full length Human SERPINA6.
Description
The serine proteinase inhibitors (serpins) comprise a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and tissue development. SerpinA6, also known as CBG or Transcortin, is a 405 amino acid Ï«-globulin secreted protein that belongs to the serpin family. Synthesized in the liver and present in glycocorticoid responsive cells, SerpinA6 functions as the primary transport protein for progestins and glucorticoids within the blood. Additionally, SerpinA6 has corticosteroid-binding properties through which it can regulate the physiological binding of serum cortisol within the cell. Defects in the gene encoding SerpinA6 are the cause of corticosteroid-binding globulin deficiency (CBG deficiency), a rare disorder characterized by reduced corticosteroid-binding rates that result in hypo/hypertension and muscle fatigue.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.