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- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 20910-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20910-1-AP, RRID:AB_10733757
- Product name
- FGD5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FGD5 antibody (Cat. #20910-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation.
VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling.
Facio-genital dysplasia-5 regulates matrix adhesion and survival of human endothelial cells.
Zhang T, Zhao C, Li Y, Wu J, Wang F, Yu J, Wang Z, Gao Y, Zhao L, Liu Y, Yan Y, Li X, Gao H, Hu Z, Cui B, Li K
Developmental cell 2024 Aug 19;59(16):2085-2100.e9
Developmental cell 2024 Aug 19;59(16):2085-2100.e9
VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.
Braun LJ, Zinnhardt M, Vockel M, Drexler HC, Peters K, Vestweber D
EMBO reports 2019 Jul;20(7):e47046
EMBO reports 2019 Jul;20(7):e47046
FGD5 Regulates VEGF Receptor-2 Coupling to PI3 Kinase and Receptor Recycling.
Farhan MA, Azad AK, Touret N, Murray AG
Arteriosclerosis, thrombosis, and vascular biology 2017 Dec;37(12):2301-2310
Arteriosclerosis, thrombosis, and vascular biology 2017 Dec;37(12):2301-2310
Facio-genital dysplasia-5 regulates matrix adhesion and survival of human endothelial cells.
Nakhaei-Nejad M, Haddad G, Zhang QX, Murray AG
Arteriosclerosis, thrombosis, and vascular biology 2012 Nov;32(11):2694-701
Arteriosclerosis, thrombosis, and vascular biology 2012 Nov;32(11):2694-701
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 20910-1-AP(FGD5 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using FGD5 antibody 20910-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung using 20910-1-AP(FGD5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung using 20910-1-AP(FGD5 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
