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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- 12797-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12797-1-AP, RRID:AB_2119687
- Product name
- HSPA2 antibody
- Antibody type
- Polyclonal
- Description
- HSPA2 antibody (Cat. #12797-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The human testis-enriched HSPA2 interacts with HIF-1α in epidermal keratinocytes, yet HIF-1α stability and HIF-1-dependent gene expression rely on the HSPA (HSP70) activity.
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours.
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline.
RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2.
Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2.
Melatonin protects the mouse testis against heat-induced damage.
Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Cigarette smoke-induced cell cycle arrest in spermatocytes [GC-2spd(ts)] is mediated through crosstalk between Ahr-Nrf2 pathway and MAPK signaling.
Molecular analysis of cell type-specific gene expression profile during mouse spermatogenesis by laser microdissection and qRT-PCR.
Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes.
Sojka DR, Gogler A, Kania D, Vydra N, Wiecha K, Adamiec-Organiściok M, Wilk A, Chumak V, Matyśniak D, Scieglinska D
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119735
Biochimica et biophysica acta. Molecular cell research 2024 Jun;1871(5):119735
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours.
Chen X, Wang S, Chen Y, Xin H, Zhang S, Wu D, Xue Y, Zha M, Li H, Li K, Gu Z, Wei W, Ping Y
Nature nanotechnology 2023 Aug;18(8):933-944
Nature nanotechnology 2023 Aug;18(8):933-944
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Zhang W, Shi B, Li S, Liu Z, Li S, Dong S, Cheng Y, Zhu J, Zhang G, Zhong M
Frontiers in endocrinology 2022;13:1041027
Frontiers in endocrinology 2022;13:1041027
Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline.
Gao L, Chang S, Xia W, Wang X, Zhang C, Cheng L, Liu X, Chen L, Shi Q, Huang J, Xu EY, Shan G
Science advances 2020 Nov;6(46)
Science advances 2020 Nov;6(46)
RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2.
Yang YL, Zhang Y, Li DD, Zhang FL, Liu HY, Liao XH, Xie HY, Lu Q, Zhang L, Hong Q, Dong WJ, Li DQ, Shao ZM
Cell death and differentiation 2020 Mar;27(3):1105-1118
Cell death and differentiation 2020 Mar;27(3):1105-1118
Various Anti-HSPA2 Antibodies Yield Different Results in Studies on Cancer-Related Functions of Heat Shock Protein A2.
Scieglinska D, Sojka DR, Gogler-Pigłowska A, Chumak V, Krawczyk Z
International journal of molecular sciences 2020 Jun 16;21(12)
International journal of molecular sciences 2020 Jun 16;21(12)
Melatonin protects the mouse testis against heat-induced damage.
Zhang P, Zheng Y, Lv Y, Li F, Su L, Qin Y, Zeng W
Molecular human reproduction 2020 Feb 29;26(2):65-79
Molecular human reproduction 2020 Feb 29;26(2):65-79
Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice.
Hu J, Sun F, Handel MA
Biology of reproduction 2018 Jan 1;98(1):102-114
Biology of reproduction 2018 Jan 1;98(1):102-114
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Cigarette smoke-induced cell cycle arrest in spermatocytes [GC-2spd(ts)] is mediated through crosstalk between Ahr-Nrf2 pathway and MAPK signaling.
Esakky P, Hansen DA, Drury AM, Moley KH
Journal of molecular cell biology 2015 Feb;7(1):73-87
Journal of molecular cell biology 2015 Feb;7(1):73-87
Molecular analysis of cell type-specific gene expression profile during mouse spermatogenesis by laser microdissection and qRT-PCR.
Esakky P, Hansen DA, Drury AM, Moley KH
Reproductive sciences (Thousand Oaks, Calif.) 2013 Mar;20(3):238-52
Reproductive sciences (Thousand Oaks, Calif.) 2013 Mar;20(3):238-52
Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes.
Sun F, Palmer K, Handel MA
Development (Cambridge, England) 2010 May;137(10):1699-707
Development (Cambridge, England) 2010 May;137(10):1699-707
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human ileum tissue were subjected to SDS PAGE followed by western blot with 12797-1-AP(HSPA2 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-HSPA2 (IP:12797-1-AP, 3ug; Detection:12797-1-AP 1:1000) with mouse skeletal muscle tissue lysate 3500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 12797-1-AP(HSPA2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 12797-1-AP(HSPA2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HSPA2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HSPA2. This antibody recognizes human,mouse,rat antigen. The HSPA2 antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.
