Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM00279G - Provider product page
- Provider
- Leading Biology
- Product name
- HSP27 (Heat Shock Protein 27) Antibody - Without BSA
- Antibody type
- Monoclonal
- Description
- This MAb reacts specifically with heat shock protein HSP27 in human and monkey tissues and cell lines such as MCF-7. HSP27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature, as well as by estrogen in hormone responsive cells. Interestingly, human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian α-crystalline lens protein. Because of the estrogen responsive nature of HSP27, this protein has been studied extensively in human estrogen responsive tissues such as cervix, endometrium and breast tissue. Therefore HSP27 may be useful in classifying various hormone sensitive tumors.
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Sheep, Simian
- Host
- Mouse
- Antibody clone number
- G3.1
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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