Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 18932-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18932-1-AP, RRID:AB_2149750
- Product name
- NDC80 antibody
- Antibody type
- Polyclonal
- Description
- NDC80 antibody (Cat. #18932-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PP6 regulation of Aurora A-TPX2 limits NDC80 phosphorylation and mitotic spindle size.
NDC80 status pinpoints mitotic kinase inhibitors as emerging therapeutic options in clear cell renal cell carcinoma.
Upregulation of nuclear division cycle 80 contributes to therapeutic resistance via the promotion of autophagy-related protein-7-dependent autophagy in lung cancer.
Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells.
Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.
Sobajima T, Kowalczyk KM, Skylakakis S, Hayward D, Fulcher LJ, Neary C, Batley C, Kurlekar S, Roberts E, Gruneberg U, Barr FA
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
NDC80 status pinpoints mitotic kinase inhibitors as emerging therapeutic options in clear cell renal cell carcinoma.
Hu C, Lin W, Zhao K, Tian G, Kong X, Luo G, Wolf DA, Cheng Y
iScience 2023 Apr 21;26(4):106531
iScience 2023 Apr 21;26(4):106531
Upregulation of nuclear division cycle 80 contributes to therapeutic resistance via the promotion of autophagy-related protein-7-dependent autophagy in lung cancer.
Chen X, He Q, Zeng S, Xu Z
Frontiers in pharmacology 2022;13:985601
Frontiers in pharmacology 2022;13:985601
Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells.
Chen YC, Chen IS, Huang GJ, Kang CH, Wang KC, Tsao MJ, Pan HW
OncoTargets and therapy 2018;11:1601-1616
OncoTargets and therapy 2018;11:1601-1616
Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.
Liu Y, Hu H, Zhang C, Wang H, Zhang W, Wang Z, Li M, Zhang W, Zhou D, Jiang T
Oncotarget 2015 Nov 10;6(35):38257-69
Oncotarget 2015 Nov 10;6(35):38257-69
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A2780 cells were subjected to SDS PAGE followed by western blot with 18932-1-AP(NDC80 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NDC80 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NDC80. This antibody recognizes human,mouse,rat antigen. The NDC80 antibody has been validated for the following applications: ELISA, WB, IHC analysis.