Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN394739 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-NDC80 Kinetochore Complex Component Homolog (S. Cerevisiae) (NDC80) (AA 545-642) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 545-642
- Isotype
- IgG
- Antibody clone number
- 1A10
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Centrosome-related genes, genetic variation, and risk of breast cancer.
Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1.
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.
siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently overexpressed in colorectal and gastric cancers, suppresses cell proliferation and induces apoptosis.
PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation.
Olson JE, Wang X, Pankratz VS, Fredericksen ZS, Vachon CM, Vierkant RA, Cerhan JR, Couch FJ
Breast cancer research and treatment 2011 Jan;125(1):221-8
Breast cancer research and treatment 2011 Jan;125(1):221-8
Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1.
Wu G, Wei R, Cheng E, Ngo B, Lee WH
Molecular biology of the cell 2009 Nov;20(22):4686-95
Molecular biology of the cell 2009 Nov;20(22):4686-95
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.
Chan YW, Fava LL, Uldschmid A, Schmitz MH, Gerlich DW, Nigg EA, Santamaria A
The Journal of cell biology 2009 Jun 1;185(5):859-74
The Journal of cell biology 2009 Jun 1;185(5):859-74
siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently overexpressed in colorectal and gastric cancers, suppresses cell proliferation and induces apoptosis.
Kaneko N, Miura K, Gu Z, Karasawa H, Ohnuma S, Sasaki H, Tsukamoto N, Yokoyama S, Yamamura A, Nagase H, Shibata C, Sasaki I, Horii A
Biochemical and biophysical research communications 2009 Dec 25;390(4):1235-40
Biochemical and biophysical research communications 2009 Dec 25;390(4):1235-40
PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation.
Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw A, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X
The Journal of biological chemistry 2009 Aug 21;284(34):23072-82
The Journal of biological chemistry 2009 Aug 21;284(34):23072-82
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC