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- Antibody Data
- Antigen structure
- References [24]
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- Product number
- FAB139P - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human NKG2D/CD314 PE-conjugated Monoclonal Antibody (Clone 149810)
- Antibody type
- Monoclonal
- Antigen
- BaF3 mouse pro-B cell line transfected with human NKG2D/CD314
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 100 Tests
Submitted references Activated hepatic stellate cells impair NK cell anti-fibrosis capacity through a TGF-β-dependent emperipolesis in HBV cirrhotic patients.
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure.
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.
Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts.
Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain.
c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.
Long-term effect on natural killer cells by interferon-α therapy on the outcomes of HCV infection.
NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors.
An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro.
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Combinatorial cytotoxicity of gemcitabine and cytokine-activated killer cells in hepatocellular carcinoma via the NKG2D-MICA/B system.
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Phenotype markers and cytokine intracellular production by CD8+ gammadelta T lymphocytes do not support a regulatory T profile in Behçet's disease patients and healthy controls.
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells.
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients.
Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity.
Endometrial NK cells are special immature cells that await pregnancy.
Endometrial NK cells are special immature cells that await pregnancy.
Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma.
Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma.
Shi J, Zhao J, Zhang X, Cheng Y, Hu J, Li Y, Zhao X, Shang Q, Sun Y, Tu B, Shi L, Gao B, Wang FS, Zhang Z
Scientific reports 2017 Mar 14;7:44544
Scientific reports 2017 Mar 14;7:44544
Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
Gill US, Peppa D, Micco L, Singh HD, Carey I, Foster GR, Maini MK, Kennedy PT
PLoS pathogens 2016 Aug;12(8):e1005788
PLoS pathogens 2016 Aug;12(8):e1005788
NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure.
Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D
PloS one 2015;10(8):e0134568
PloS one 2015;10(8):e0134568
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.
Kruse V, Hamann C, Monecke S, Cyganek L, Elsner L, Hübscher D, Walter L, Streckfuss-Bömeke K, Guan K, Dressel R
PloS one 2015;10(5):e0125544
PloS one 2015;10(5):e0125544
Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts.
Picardi A, Mengarelli A, Marino M, Gallo E, Benevolo M, Pescarmona E, Cocco R, Fraioli R, Tremante E, Petti MC, De Fabritiis P, Giacomini P
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:98
Journal of experimental & clinical cancer research : CR 2015 Sep 11;34:98
Natural killer (NK) cells inhibit systemic metastasis of glioblastoma cells and have therapeutic effects against glioblastomas in the brain.
Lee SJ, Kang WY, Yoon Y, Jin JY, Song HJ, Her JH, Kang SM, Hwang YK, Kang KJ, Joo KM, Nam DH
BMC cancer 2015 Dec 24;15:1011
BMC cancer 2015 Dec 24;15:1011
c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.
Molfetta R, Quatrini L, Capuano C, Gasparrini F, Zitti B, Zingoni A, Galandrini R, Santoni A, Paolini R
European journal of immunology 2014 Sep;44(9):2761-70
European journal of immunology 2014 Sep;44(9):2761-70
Long-term effect on natural killer cells by interferon-α therapy on the outcomes of HCV infection.
Hu X, Jiang Y, Li X, Gao Y, Guo X, Chi X, Yan H, Feng J, Zhong J, Sun B, Shao X, Xiao W, Pan Y, Niu J
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2014 May;34(5):366-75
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2014 May;34(5):366-75
NKG2D-directed cytokine-activated killer lymphocyte therapy combined with gemcitabine for patients with chemoresistant metastatic solid tumors.
Morisaki T, Hirano T, Koya N, Kiyota A, Tanaka H, Umebayashi M, Onishi H, Katano M
Anticancer research 2014 Aug;34(8):4529-38
Anticancer research 2014 Aug;34(8):4529-38
An epithelial cell adhesion molecule- and CD3-bispecific antibody plus activated T-cells can eradicate chemoresistant cancer stem-like pancreatic carcinoma cells in vitro.
Umebayashi M, Kiyota A, Koya N, Tanaka H, Onishi H, Katano M, Morisaki T
Anticancer research 2014 Aug;34(8):4509-19
Anticancer research 2014 Aug;34(8):4509-19
Natural killer cells are characterized by the concomitantly increased interferon-γ and cytotoxicity in acute resolved hepatitis B patients.
Zhao J, Li Y, Jin L, Zhang S, Fan R, Sun Y, Zhou C, Shang Q, Li W, Zhang Z, Wang FS
PloS one 2012;7(11):e49135
PloS one 2012;7(11):e49135
Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Qin H, Lee IF, Panagiotopoulos C, Wang X, Chu AD, Utz PJ, Priatel JJ, Tan R
Diabetes 2011 Mar;60(3):857-66
Diabetes 2011 Mar;60(3):857-66
Combinatorial cytotoxicity of gemcitabine and cytokine-activated killer cells in hepatocellular carcinoma via the NKG2D-MICA/B system.
Morisaki T, Onishi H, Koya N, Kiyota A, Tanaka H, Umebayashi M, Ogino T, Nagamatsu I, Katano M
Anticancer research 2011 Jul;31(7):2505-10
Anticancer research 2011 Jul;31(7):2505-10
Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry.
Llinàs L, Lázaro A, de Salort J, Matesanz-Isabel J, Sintes J, Engel P
Immunology letters 2011 Jan 30;134(2):113-21
Immunology letters 2011 Jan 30;134(2):113-21
Phenotype markers and cytokine intracellular production by CD8+ gammadelta T lymphocytes do not support a regulatory T profile in Behçet's disease patients and healthy controls.
Clemente A, Cambra A, Munoz-Saá I, Crespí C, Pallarés L, Juan A, Matamoros N, Julià MR
Immunology letters 2010 Apr 8;129(2):57-63
Immunology letters 2010 Apr 8;129(2):57-63
Expression of the ULBP ligands for NKG2D by B-NHL cells plays an important role in determining their susceptibility to rituximab-induced ADCC.
Inagaki A, Ishida T, Yano H, Ishii T, Kusumoto S, Ito A, Ri M, Mori F, Ding J, Komatsu H, Iida S, Ueda R
International journal of cancer 2009 Jul 1;125(1):212-21
International journal of cancer 2009 Jul 1;125(1):212-21
4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells.
Kim YJ, Han MK, Broxmeyer HE
Blood 2008 Feb 1;111(3):1378-86
Blood 2008 Feb 1;111(3):1378-86
Binding of excreted and/or secreted products of adult hookworms to human NK cells in Necator americanus-infected individuals from Brazil.
Teixeira-Carvalho A, Fujiwara RT, Stemmy EJ, Olive D, Damsker JM, Loukas A, Corrêa-Oliveira R, Constant SL, Bethony JM
Infection and immunity 2008 Dec;76(12):5810-6
Infection and immunity 2008 Dec;76(12):5810-6
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients.
Cai L, Zhang Z, Zhou L, Wang H, Fu J, Zhang S, Shi M, Zhang H, Yang Y, Wu H, Tien P, Wang FS
Clinical immunology (Orlando, Fla.) 2008 Dec;129(3):428-37
Clinical immunology (Orlando, Fla.) 2008 Dec;129(3):428-37
Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity.
Kwong KY, Baskar S, Zhang H, Mackall CL, Rader C
Journal of molecular biology 2008 Dec 31;384(5):1143-56
Journal of molecular biology 2008 Dec 31;384(5):1143-56
Endometrial NK cells are special immature cells that await pregnancy.
Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Endometrial NK cells are special immature cells that await pregnancy.
Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):1869-76
Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma.
Viey E, Fromont G, Escudier B, Morel Y, Da Rocha S, Chouaib S, Caignard A
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1338-47
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1338-47
Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma.
Viey E, Fromont G, Escudier B, Morel Y, Da Rocha S, Chouaib S, Caignard A
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1338-47
Journal of immunology (Baltimore, Md. : 1950) 2005 Feb 1;174(3):1338-47
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