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- References [60]
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- Product number
- MAB139 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human NKG2D/CD314 Monoclonal Antibody (Clone 149810)
- Antibody type
- Monoclonal
- Antigen
- BaF3 mouse pro-B cell line transfected with human NKG2D/CD314
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Control of Tumor Initiation by NKG2D Naturally Expressed on Ovarian Cancer Cells.
Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells.
Prognostic significance and functional implication of immune activating receptor NKG2D in gastric cancer.
Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System.
Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma.
CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells.
EBI3 regulates the NK cell response to mouse cytomegalovirus infection.
Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20.
NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.
A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers.
SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice.
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.
Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids.
Central nervous system acute lymphoblastic leukemia: role of natural killer cells.
Natural killer cells induce eosinophil activation and apoptosis.
L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration.
c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.
A truncated human NKG2D splice isoform negatively regulates NKG2D-mediated function.
Dok1 and Dok2 proteins regulate natural killer cell development and function.
Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas.
CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.
Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation.
Mechanisms of the antitumor activity of human Vγ9Vδ2 T cells in combination with zoledronic acid in a preclinical model of neuroblastoma.
A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions.
The road to memory: an early rest for the long journey.
Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy.
Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity.
Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A.
MiR-10b downregulates the stress-induced cell surface molecule MICB, a critical ligand for cancer cell recognition by natural killer cells.
Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins.
Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes.
Human TCRγδ+ T cells represent a novel target for IL-27 activity.
NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner.
Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D.
2-deoxy D-glucose prevents cell surface expression of NKG2D ligands through inhibition of N-linked glycosylation.
Wiskott-Aldrich syndrome protein (WASp) and N-WASp are involved in the regulation of NK-cell migration upon NKG2D activation.
Potent anti-tumor killing activity of the multifunctional Treg cell line HOZOT against human tumors with diverse origins.
DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction.
Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells.
Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement.
Cytotoxicity of activated natural killer cells against pediatric solid tumors.
Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells.
Detuning CD8+ T lymphocytes by down-regulation of the activating receptor NKG2D: role of NKG2D ligands released by activated T cells.
SHP-2 expression negatively regulates NK cell function.
Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells.
NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways.
Induction of MHC class I-related chain B (MICB) by 5-aza-2'-deoxycytidine.
4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells.
Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma.
Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity.
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy.
4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy.
Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function.
BCR/ABL promotes dendritic cell-mediated natural killer cell activation.
Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104.
Cai X, Caballero-Benitez A, Gewe MM, Jenkins IC, Drescher CW, Strong RK, Spies T, Groh V
Neoplasia (New York, N.Y.) 2017 Jun;19(6):471-482
Neoplasia (New York, N.Y.) 2017 Jun;19(6):471-482
Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells.
Djaoud Z, Guethlein LA, Horowitz A, Azzi T, Nemat-Gorgani N, Olive D, Nadal D, Norman PJ, Münz C, Parham P
The Journal of experimental medicine 2017 Jun 5;214(6):1827-1841
The Journal of experimental medicine 2017 Jun 5;214(6):1827-1841
Prognostic significance and functional implication of immune activating receptor NKG2D in gastric cancer.
Lin F, Dai C, Ge X, Tang W, Lin Y, Wang Y, Li J
Biochemical and biophysical research communications 2017 Jun 3;487(3):619-624
Biochemical and biophysical research communications 2017 Jun 3;487(3):619-624
Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System.
Santaguida S, Richardson A, Iyer DR, M'Saad O, Zasadil L, Knouse KA, Wong YL, Rhind N, Desai A, Amon A
Developmental cell 2017 Jun 19;41(6):638-651.e5
Developmental cell 2017 Jun 19;41(6):638-651.e5
Low-dose bortezomib increases the expression of NKG2D and DNAM-1 ligands and enhances induced NK and γδ T cell-mediated lysis in multiple myeloma.
Niu C, Jin H, Li M, Zhu S, Zhou L, Jin F, Zhou Y, Xu D, Xu J, Zhao L, Hao S, Li W, Cui J
Oncotarget 2017 Jan 24;8(4):5954-5964
Oncotarget 2017 Jan 24;8(4):5954-5964
CD155 on HIV-Infected Cells Is Not Modulated by HIV-1 Vpu and Nef but Synergizes with NKG2D Ligands to Trigger NK Cell Lysis of Autologous Primary HIV-Infected Cells.
Davis ZB, Sowrirajan B, Cogswell A, Ward JP, Planelles V, Barker E
AIDS research and human retroviruses 2017 Feb;33(2):93-100
AIDS research and human retroviruses 2017 Feb;33(2):93-100
EBI3 regulates the NK cell response to mouse cytomegalovirus infection.
Jensen H, Chen SY, Folkersen L, Nolan GP, Lanier LL
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 14;114(7):1625-1630
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 14;114(7):1625-1630
Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20.
Charpak-Amikam Y, Kubsch T, Seidel E, Oiknine-Djian E, Cavaletto N, Yamin R, Schmiedel D, Wolf D, Gribaudo G, Messerle M, Cicin-Sain L, Mandelboim O
Scientific reports 2017 Aug 17;7(1):8661
Scientific reports 2017 Aug 17;7(1):8661
NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.
Parry HM, Stevens T, Oldreive C, Zadran B, McSkeane T, Rudzki Z, Paneesha S, Chadwick C, Stankovic T, Pratt G, Zuo J, Moss P
Oncotarget 2016 Oct 18;7(42):68513-68526
Oncotarget 2016 Oct 18;7(42):68513-68526
A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers.
Espinoza JL, Nguyen VH, Ichimura H, Pham TT, Nguyen CH, Pham TV, Elbadry MI, Yoshioka K, Tanaka J, Trung LQ, Takami A, Nakao S
Scientific reports 2016 Dec 20;6:39231
Scientific reports 2016 Dec 20;6:39231
SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice.
Ke M, Wang H, Zhou Y, Li J, Liu Y, Zhang M, Dou J, Xi T, Shen B, Zhou C
Oncotarget 2016 Aug 2;7(31):49509-49526
Oncotarget 2016 Aug 2;7(31):49509-49526
Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.
Kruse V, Hamann C, Monecke S, Cyganek L, Elsner L, Hübscher D, Walter L, Streckfuss-Bömeke K, Guan K, Dressel R
PloS one 2015;10(5):e0125544
PloS one 2015;10(5):e0125544
Cytotoxicity and infiltration of human NK cells in in vivo-like tumor spheroids.
Giannattasio A, Weil S, Kloess S, Ansari N, Stelzer EH, Cerwenka A, Steinle A, Koehl U, Koch J
BMC cancer 2015 May 3;15:351
BMC cancer 2015 May 3;15:351
Central nervous system acute lymphoblastic leukemia: role of natural killer cells.
Frishman-Levy L, Shemesh A, Bar-Sinai A, Ma C, Ni Z, Frenkel S, Muench V, Bruckmueller H, Vokuhl C, Debatin KM, Eckert C, Stanulla M, Schrappe M, Campbell KS, Loewenthal R, Schewe DM, Hochman J, Meyer LH, Kaufman D, Cario G, Porgador A, Izraeli S
Blood 2015 May 28;125(22):3420-31
Blood 2015 May 28;125(22):3420-31
Natural killer cells induce eosinophil activation and apoptosis.
Awad A, Yassine H, Barrier M, Vorng H, Marquillies P, Tsicopoulos A, Duez C
PloS one 2014;9(4):e94492
PloS one 2014;9(4):e94492
L-plastin is involved in NKG2D recruitment into lipid rafts and NKG2D-mediated NK cell migration.
Serrano-Pertierra E, Cernuda-Morollón E, Brdička T, Hoøejši V, López-Larrea C
Journal of leukocyte biology 2014 Sep;96(3):437-45
Journal of leukocyte biology 2014 Sep;96(3):437-45
c-Cbl regulates MICA- but not ULBP2-induced NKG2D down-modulation in human NK cells.
Molfetta R, Quatrini L, Capuano C, Gasparrini F, Zitti B, Zingoni A, Galandrini R, Santoni A, Paolini R
European journal of immunology 2014 Sep;44(9):2761-70
European journal of immunology 2014 Sep;44(9):2761-70
A truncated human NKG2D splice isoform negatively regulates NKG2D-mediated function.
Karimi MA, Aguilar O, Zou B, Bachmann MH, Carlyle JR, Baldwin CL, Kambayashi T
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 15;193(6):2764-2771
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 15;193(6):2764-2771
Dok1 and Dok2 proteins regulate natural killer cell development and function.
Celis-Gutierrez J, Boyron M, Walzer T, Pandolfi PP, Jonjić S, Olive D, Dalod M, Vivier E, Nunès JA
The EMBO journal 2014 Sep 1;33(17):1928-40
The EMBO journal 2014 Sep 1;33(17):1928-40
Cytokine-induced killer cells eradicate bone and soft-tissue sarcomas.
Sangiolo D, Mesiano G, Gammaitoni L, Leuci V, Todorovic M, Giraudo L, Cammarata C, Dell'Aglio C, D'Ambrosio L, Pisacane A, Sarotto I, Miano S, Ferrero I, Carnevale-Schianca F, Pignochino Y, Sassi F, Bertotti A, Piacibello W, Fagioli F, Aglietta M, Grignani G
Cancer research 2014 Jan 1;74(1):119-29
Cancer research 2014 Jan 1;74(1):119-29
CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signaling.
Hosomi S, Chen Z, Baker K, Chen L, Huang YH, Olszak T, Zeissig S, Wang JH, Mandelboim O, Beauchemin N, Lanier LL, Blumberg RS
European journal of immunology 2013 Sep;43(9):2473-83
European journal of immunology 2013 Sep;43(9):2473-83
Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation.
Leung WH, Vong QP, Lin W, Janke L, Chen T, Leung W
The Journal of experimental medicine 2013 Nov 18;210(12):2675-92
The Journal of experimental medicine 2013 Nov 18;210(12):2675-92
Mechanisms of the antitumor activity of human Vγ9Vδ2 T cells in combination with zoledronic acid in a preclinical model of neuroblastoma.
Di Carlo E, Bocca P, Emionite L, Cilli M, Cipollone G, Morandi F, Raffaghello L, Pistoia V, Prigione I
Molecular therapy : the journal of the American Society of Gene Therapy 2013 May;21(5):1034-43
Molecular therapy : the journal of the American Society of Gene Therapy 2013 May;21(5):1034-43
A unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions.
Windheim M, Southcombe JH, Kremmer E, Chaplin L, Urlaub D, Falk CS, Claus M, Mihm J, Braithwaite M, Dennehy K, Renz H, Sester M, Watzl C, Burgert HG
Proceedings of the National Academy of Sciences of the United States of America 2013 Dec 10;110(50):E4884-93
Proceedings of the National Academy of Sciences of the United States of America 2013 Dec 10;110(50):E4884-93
The road to memory: an early rest for the long journey.
Ho LP, Yit PS, Ng LH, Linn YC, Zhao Y, Sun L, Ling KL, Chai Koh MB, Monica Shih MC, Li S, Wang XY, Tien SL, Goh YT
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5603-14
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5603-14
Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy.
Lim SA, Kim TJ, Lee JE, Sonn CH, Kim K, Kim J, Choi JG, Choi IK, Yun CO, Kim JH, Yee C, Kumar V, Lee KM
Cancer research 2013 Apr 15;73(8):2598-607
Cancer research 2013 Apr 15;73(8):2598-607
Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity.
Ham H, Guerrier S, Kim J, Schoon RA, Anderson EL, Hamann MJ, Lou Z, Billadeau DD
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 1;190(7):3661-9
Journal of immunology (Baltimore, Md. : 1950) 2013 Apr 1;190(7):3661-9
Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A.
Nielsen N, Ødum N, Ursø B, Lanier LL, Spee P
PloS one 2012;7(2):e31959
PloS one 2012;7(2):e31959
MiR-10b downregulates the stress-induced cell surface molecule MICB, a critical ligand for cancer cell recognition by natural killer cells.
Tsukerman P, Stern-Ginossar N, Gur C, Glasner A, Nachmani D, Bauman Y, Yamin R, Vitenshtein A, Stanietsky N, Bar-Mag T, Lankry D, Mandelboim O
Cancer research 2012 Nov 1;72(21):5463-72
Cancer research 2012 Nov 1;72(21):5463-72
Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins.
Brown AC, Dobbie IM, Alakoskela JM, Davis I, Davis DM
Blood 2012 Nov 1;120(18):3729-40
Blood 2012 Nov 1;120(18):3729-40
Analysis of Vδ1 T cells in clinical grade melanoma-infiltrating lymphocytes.
Donia M, Ellebaek E, Andersen MH, Straten PT, Svane IM
Oncoimmunology 2012 Nov 1;1(8):1297-1304
Oncoimmunology 2012 Nov 1;1(8):1297-1304
Human TCRγδ+ T cells represent a novel target for IL-27 activity.
Morandi F, Prigione I, Airoldi I
European journal of immunology 2012 Jun;42(6):1547-52
European journal of immunology 2012 Jun;42(6):1547-52
NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner.
Glässner A, Eisenhardt M, Krämer B, Körner C, Coenen M, Sauerbruch T, Spengler U, Nattermann J
Laboratory investigation; a journal of technical methods and pathology 2012 Jul;92(7):967-77
Laboratory investigation; a journal of technical methods and pathology 2012 Jul;92(7):967-77
Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D.
Heinemann A, Zhao F, Pechlivanis S, Eberle J, Steinle A, Diederichs S, Schadendorf D, Paschen A
Cancer research 2012 Jan 15;72(2):460-71
Cancer research 2012 Jan 15;72(2):460-71
2-deoxy D-glucose prevents cell surface expression of NKG2D ligands through inhibition of N-linked glycosylation.
Andresen L, Skovbakke SL, Persson G, Hagemann-Jensen M, Hansen KA, Jensen H, Skov S
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1847-55
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1847-55
Wiskott-Aldrich syndrome protein (WASp) and N-WASp are involved in the regulation of NK-cell migration upon NKG2D activation.
Serrano-Pertierra E, Cernuda-Morollón E, López-Larrea C
European journal of immunology 2012 Aug;42(8):2142-51
European journal of immunology 2012 Aug;42(8):2142-51
Potent anti-tumor killing activity of the multifunctional Treg cell line HOZOT against human tumors with diverse origins.
Inoue T, Tashiro Y, Takeuchi M, Otani T, Tsuji-Takayama K, Okochi A, Mukae Y, Koreishi M, Yamasaki F, Kumon H, Nakamura S, Kibata M, Kondo E
International journal of oncology 2011 May;38(5):1299-306
International journal of oncology 2011 May;38(5):1299-306
DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction.
Ardolino M, Zingoni A, Cerboni C, Cecere F, Soriani A, Iannitto ML, Santoni A
Blood 2011 May 5;117(18):4778-86
Blood 2011 May 5;117(18):4778-86
Natural killer cells from children with type 1 diabetes have defects in NKG2D-dependent function and signaling.
Qin H, Lee IF, Panagiotopoulos C, Wang X, Chu AD, Utz PJ, Priatel JJ, Tan R
Diabetes 2011 Mar;60(3):857-66
Diabetes 2011 Mar;60(3):857-66
NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease.
Angelini DF, Zambello R, Galandrini R, Diamantini A, Placido R, Micucci F, Poccia F, Semenzato G, Borsellino G, Santoni A, Battistini L
Journal of leukocyte biology 2011 Jan;89(1):75-84
Journal of leukocyte biology 2011 Jan;89(1):75-84
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells.
Cabezón R, Sintes J, Llinàs L, Benitez-Ribas D
Immunology letters 2011 Jan 30;134(2):167-73
Immunology letters 2011 Jan 30;134(2):167-73
Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement.
Maniar A, Zhang X, Lin W, Gastman BR, Pauza CD, Strome SE, Chapoval AI
Blood 2010 Sep 9;116(10):1726-33
Blood 2010 Sep 9;116(10):1726-33
Cytotoxicity of activated natural killer cells against pediatric solid tumors.
Cho D, Shook DR, Shimasaki N, Chang YH, Fujisaki H, Campana D
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Aug 1;16(15):3901-9
Clinical cancer research : an official journal of the American Association for Cancer Research 2010 Aug 1;16(15):3901-9
Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells.
Markel G, Seidman R, Besser MJ, Zabari N, Ortenberg R, Shapira R, Treves AJ, Loewenthal R, Orenstein A, Nagler A, Schachter J
PloS one 2009;4(5):e5597
PloS one 2009;4(5):e5597
Detuning CD8+ T lymphocytes by down-regulation of the activating receptor NKG2D: role of NKG2D ligands released by activated T cells.
Cerboni C, Ardolino M, Santoni A, Zingoni A
Blood 2009 Mar 26;113(13):2955-64
Blood 2009 Mar 26;113(13):2955-64
SHP-2 expression negatively regulates NK cell function.
Purdy AK, Campbell KS
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 1;183(11):7234-43
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 1;183(11):7234-43
Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells.
Schwinn N, Vokhminova D, Sucker A, Textor S, Striegel S, Moll I, Nausch N, Tuettenberg J, Steinle A, Cerwenka A, Schadendorf D, Paschen A
International journal of cancer 2009 Apr 1;124(7):1594-604
International journal of cancer 2009 Apr 1;124(7):1594-604
NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways.
Verhoeven DH, de Hooge AS, Mooiman EC, Santos SJ, ten Dam MM, Gelderblom H, Melief CJ, Hogendoorn PC, Egeler RM, van Tol MJ, Schilham MW, Lankester AC
Molecular immunology 2008 Sep;45(15):3917-25
Molecular immunology 2008 Sep;45(15):3917-25
Induction of MHC class I-related chain B (MICB) by 5-aza-2'-deoxycytidine.
Tang KF, He CX, Zeng GL, Wu J, Song GB, Shi YS, Zhang WG, Huang AL, Steinle A, Ren H
Biochemical and biophysical research communications 2008 Jun 13;370(4):578-83
Biochemical and biophysical research communications 2008 Jun 13;370(4):578-83
4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells.
Kim YJ, Han MK, Broxmeyer HE
Blood 2008 Feb 1;111(3):1378-86
Blood 2008 Feb 1;111(3):1378-86
Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma.
Shi J, Tricot GJ, Garg TK, Malaviarachchi PA, Szmania SM, Kellum RE, Storrie B, Mulder A, Shaughnessy JD Jr, Barlogie B, van Rhee F
Blood 2008 Feb 1;111(3):1309-17
Blood 2008 Feb 1;111(3):1309-17
Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity.
Kwong KY, Baskar S, Zhang H, Mackall CL, Rader C
Journal of molecular biology 2008 Dec 31;384(5):1143-56
Journal of molecular biology 2008 Dec 31;384(5):1143-56
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
Dulphy N, Haas P, Busson M, Belhadj S, Peffault de Latour R, Robin M, Carmagnat M, Loiseau P, Tamouza R, Scieux C, Rabian C, Di Santo JP, Charron D, Janin A, Socié G, Toubert A
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):2227-37
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):2227-37
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.
Dulphy N, Haas P, Busson M, Belhadj S, Peffault de Latour R, Robin M, Carmagnat M, Loiseau P, Tamouza R, Scieux C, Rabian C, Di Santo JP, Charron D, Janin A, Socié G, Toubert A
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):2227-37
Journal of immunology (Baltimore, Md. : 1950) 2008 Aug 1;181(3):2227-37
4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy.
Zhang H, Snyder KM, Suhoski MM, Maus MV, Kapoor V, June CH, Mackall CL
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 1;179(7):4910-8
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 1;179(7):4910-8
4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy.
Zhang H, Snyder KM, Suhoski MM, Maus MV, Kapoor V, June CH, Mackall CL
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 1;179(7):4910-8
Journal of immunology (Baltimore, Md. : 1950) 2007 Oct 1;179(7):4910-8
Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
Hanabuchi S, Watanabe N, Wang YH, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
Blood 2006 May 1;107(9):3617-23
Blood 2006 May 1;107(9):3617-23
Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function.
Roda-Navarro P, Vales-Gomez M, Chisholm SE, Reyburn HT
Proceedings of the National Academy of Sciences of the United States of America 2006 Jul 25;103(30):11258-63
Proceedings of the National Academy of Sciences of the United States of America 2006 Jul 25;103(30):11258-63
BCR/ABL promotes dendritic cell-mediated natural killer cell activation.
Terme M, Borg C, Guilhot F, Masurier C, Flament C, Wagner EF, Caillat-Zucman S, Bernheim A, Turhan AG, Caignard A, Zitvogel L
Cancer research 2005 Jul 15;65(14):6409-17
Cancer research 2005 Jul 15;65(14):6409-17
Receptors and lytic mediators regulating anti-tumor activity by the leukemic killer T cell line TALL-104.
Brando C, Mukhopadhyay S, Kovacs E, Medina R, Patel P, Catina TL, Campbell KS, Santoli D
Journal of leukocyte biology 2005 Aug;78(2):359-71
Journal of leukocyte biology 2005 Aug;78(2):359-71
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