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- Antigen structure
- References [16]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21535-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21535-1-AP, RRID:AB_10732960
- Product name
- FOXO4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated FOXO4 antibody (Cat. #21535-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tumor-derived extracellular vesicles delivering TNF-α promotes colorectal cancer metastasis via the NF-kB/LAMB3/AKT axis by targeting SNAP23.
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation.
Sodium Butyrate Induces Mitophagy and Apoptosis of Bovine Skeletal Muscle Satellite Cells through the Mammalian Target of Rapamycin Signaling Pathway.
Ultra-small polydopamine nanomedicine-enabled antioxidation against senescence.
Virus-induced FoxO factor facilitates replication of human cytomegalovirus.
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction.
Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
FOXO4 expression associates with glioblastoma development and FOXO4 expression inhibits cell malignant phenotypes in vitro and in vivo.
miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4.
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies.
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Xie BW, Guan B, Chen W, Zhou M, Gu Q, Liu Y, Yan D
Archives of biochemistry and biophysics 2023 Jun;741:109605
Archives of biochemistry and biophysics 2023 Jun;741:109605
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cheng L, He Q, Liu B, Chen L, Lv F, Li X, Li Y, Liu C, Song Y, Xing Y
Cell death & disease 2023 Jan 31;14(1):74
Cell death & disease 2023 Jan 31;14(1):74
The AKT1-FOXO4 axis reciprocally regulates hemochorial placentation.
Kozai K, Moreno-Irusta A, Iqbal K, Winchester ML, Scott RL, Simon ME, Muto M, Parrish MR, Soares MJ
Development (Cambridge, England) 2023 Jan 15;150(2)
Development (Cambridge, England) 2023 Jan 15;150(2)
Sodium Butyrate Induces Mitophagy and Apoptosis of Bovine Skeletal Muscle Satellite Cells through the Mammalian Target of Rapamycin Signaling Pathway.
Ding Y, Wang P, Li C, Zhang Y, Yang C, Zhou X, Wang X, Su Z, Ming W, Zeng L, Shi Y, Li CJ, Kang X
International journal of molecular sciences 2023 Aug 30;24(17)
International journal of molecular sciences 2023 Aug 30;24(17)
Ultra-small polydopamine nanomedicine-enabled antioxidation against senescence.
Han J, Wang J, Shi H, Li Q, Zhang S, Wu H, Li W, Gan L, Brown-Borg HM, Feng W, Chen Y, Zhao RC
Materials today. Bio 2023 Apr;19:100544
Materials today. Bio 2023 Apr;19:100544
Virus-induced FoxO factor facilitates replication of human cytomegalovirus.
Sleman S
Archives of virology 2022 Jan;167(1):109-121
Archives of virology 2022 Jan;167(1):109-121
Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.
Jie W, Rui-Fen Z, Zhong-Xiang H, Yan W, Wei-Na L, Yong-Ping M, Jing S, Jing-Yi C, Wan-Hong L, Xiao-Hua H, Zhi L, Yan S
Virulence 2022 Dec;13(1):342-354
Virulence 2022 Dec;13(1):342-354
Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction.
Li H, Zhu J, Xu YW, Mou FF, Shan XL, Wang QL, Liu BN, Ning K, Liu JJ, Wang YC, Mi JX, Wei X, Shao SJ, Cui GH, Lu R, Guo HD
Redox biology 2022 Aug;54:102384
Redox biology 2022 Aug;54:102384
Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors.
Xia W, Xie J, Cai Z, Liu X, Wen J, Cui ZK, Zhao R, Zhou X, Chen J, Mao X, Gu Z, Zou Z, Zou Z, Zhang Y, Zhao M, Mac M, Song Q, Bai X
Nature communications 2021 Oct 15;12(1):6043
Nature communications 2021 Oct 15;12(1):6043
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Yang S, Zhao N, Sun B, Yang Y, Hu Y, Zhao R
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
FOXO4 expression associates with glioblastoma development and FOXO4 expression inhibits cell malignant phenotypes in vitro and in vivo.
Qi M, Sun LA, Jiang XC, Han YL, Wang L, Niu WH, Fei MX, Zhaba WD, Zheng LR, Zhou ML
Life sciences 2020 Apr 15;247:117436
Life sciences 2020 Apr 15;247:117436
miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4.
Chen S, Zhang JY, Sun LS, Li XF, Bai JY, Zhang HY, Li TJ
OncoTargets and therapy 2019;12:11425-11436
OncoTargets and therapy 2019;12:11425-11436
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies.
Auguste G, Gurha P, Lombardi R, Coarfa C, Willerson JT, Marian AJ
Circulation research 2018 Mar 2;122(5):678-692
Circulation research 2018 Mar 2;122(5):678-692
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
Yang Y, Li X, Sun Q, He B, Jia Y, Cai D, Zhao R
The international journal of biochemistry & cell biology 2016 Oct;79:222-230
The international journal of biochemistry & cell biology 2016 Oct;79:222-230
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Xu X, Fan Z, Kang L, Han J, Jiang C, Zheng X, Zhu Z, Jiao H, Lin J, Jiang K, Ding L, Zhang H, Cheng L, Fu H, Song Y, Jiang Y, Liu J, Wang R, Du N, Ye Q
The Journal of clinical investigation 2013 Feb;123(2):630-45
The Journal of clinical investigation 2013 Feb;123(2):630-45
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 21535-1-AP(FOXO4 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 21535-1-AP(FOXO4 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FOXO4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human FOXO4. This antibody recognizes human,mouse,rat antigen. The FOXO4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
