ABIN362126

antibody from antibodies-online

Targeting: FOXO4 AFX1, MLLT7

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362126

Provider

antibodies-online

Product name

anti-Forkhead Box O4 (FOXO4) (pSer197) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer197 (A-A-S (p) -M-D) derived from Human AFX. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer197

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M
Cell death and differentiation 2005 Jun;12(6):668-77

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Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

Brownawell AM, Kops GJ, Macara IG, Burgering BM
Molecular and cellular biology 2001 May;21(10):3534-46

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Direct control of the Forkhead transcription factor AFX by protein kinase B.

Kops GJ, de Ruiter ND, De Vries-Smits AM, Powell DR, Bos JL, Burgering BM
Nature 1999 Apr 15;398(6728):630-4