Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2840637 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Forkhead Box O4 (FOXO4) (AA 44-73), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 44-73, N-Term
- Antibody clone number
- RB2253
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1.
The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism.
MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function.
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors.
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.
Crossley LJ
Journal of leukocyte biology 2003 Oct;74(4):583-92
Journal of leukocyte biology 2003 Oct;74(4):583-92
The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism.
Tang TT, Lasky LA
The Journal of biological chemistry 2003 Aug 8;278(32):30125-35
The Journal of biological chemistry 2003 Aug 8;278(32):30125-35
MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function.
So CW, Cleary ML
Molecular and cellular biology 2002 Sep;22(18):6542-52
Molecular and cellular biology 2002 Sep;22(18):6542-52
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors.
Kops GJ, Medema RH, Glassford J, Essers MA, Dijkers PF, Coffer PJ, Lam EW, Burgering BM
Molecular and cellular biology 2002 Apr;22(7):2025-36
Molecular and cellular biology 2002 Apr;22(7):2025-36
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.
Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL, Lasky LA
The Journal of biological chemistry 2002 Apr 19;277(16):14255-65
The Journal of biological chemistry 2002 Apr 19;277(16):14255-65
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC