Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN658930 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Forkhead Box O4 (FOXO4) (pSer197) antibody
- Antibody type
- Polyclonal
- Description
- The antibody was affinity-purified from rabbit antiserum using epitope-specific phosphopeptide column, and the antibody against non-phosphopeptide was removed using non-phosphopeptide column corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer197
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
- Handling
- Avoid freeze-thaw cycles.
Submitted references Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake.
PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.
O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress.
FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation.
14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.
Zhu J, Mounzih K, Chehab EF, Mitro N, Saez E, Chehab FF
Journal of lipid research 2010 Jun;51(6):1312-24
Journal of lipid research 2010 Jun;51(6):1312-24
PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4.
Kwon IK, Wang R, Thangaraju M, Shuang H, Liu K, Dashwood R, Dulin N, Ganapathy V, Browning DD
Oncogene 2010 Jun 10;29(23):3423-34
Oncogene 2010 Jun 10;29(23):3423-34
O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress.
Ho SR, Wang K, Whisenhunt TR, Huang P, Zhu X, Kudlow JE, Paterson AJ
FEBS letters 2010 Jan 4;584(1):49-54
FEBS letters 2010 Jan 4;584(1):49-54
FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation.
Zhou W, Cao Q, Peng Y, Zhang QJ, Castrillon DH, DePinho RA, Liu ZP
Gastroenterology 2009 Oct;137(4):1403-14
Gastroenterology 2009 Oct;137(4):1403-14
14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.
Silhan J, Vacha P, Strnadova P, Vecer J, Herman P, Sulc M, Teisinger J, Obsilova V, Obsil T
The Journal of biological chemistry 2009 Jul 17;284(29):19349-60
The Journal of biological chemistry 2009 Jul 17;284(29):19349-60
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC