Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN400798 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (pSer457) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human, Mouse, Rat, Xenopus
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 9G6
- Vial size
- 25 µL
- Concentration
- 0.7 mg/ml (by UV absorbance at 280 nm)
- Storage
- Store the antibody at 2 °C to 8 °C up to one month or (in aliquots) at -20 °C to -70 °C forlonger. To minimize loss of volume (25µl) dilute 1: 10 by adding 225 µl of the buffer statedabove directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect thevolume at the bottom of the vial. Use this intermediate dilution when calculating finaldilutions. Avoid repeated freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Shelf life: one year from despatch.
Submitted references Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion.
Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.
Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.
Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A, Horiuchi D, Lebbink RJ, Mo YY, Goga A, McManus MT
The Journal of biological chemistry 2009 Jul 3;284(27):18515-24
The Journal of biological chemistry 2009 Jul 3;284(27):18515-24
Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.
Jansen AP, Camalier CE, Colburn NH
Cancer research 2005 Jul 15;65(14):6034-41
Cancer research 2005 Jul 15;65(14):6034-41
Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.
Palamarchuk A, Efanov A, Maximov V, Aqeilan RI, Croce CM, Pekarsky Y
Cancer research 2005 Dec 15;65(24):11282-6
Cancer research 2005 Dec 15;65(24):11282-6
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Western Blotting
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Immunohistochemistry