HPA024185

antibody from Atlas Antibodies

Targeting: RBCK1 C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4

Western blot (Data presented on provider website)

Antibody Data

Product number

HPA024185

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA024185, RRID:AB_1845673

Product name

Anti-RBCK1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human RBCK1, Gene description: RanBP-type and C3HC4-type zinc finger containing 1, Alternative Gene Names: C20orf18, HOIL1, RBCK2, RNF54, UBCE7IP3, XAP4, ZRANB4, Validated applications: WB, Uniprot ID: Q9BYM8, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis

Fu Y, Li L, Zhang X, Deng Z, Wu Y, Chen W, Liu Y, He S, Wang J, Xie Y, Tu Z, Lyu Y, Wei Y, Wang S, Cui C, Liu C, Zhang L
Nature Communications 2024;15(1)

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Enforced CARD11/MALT1 signaling in dendritic cells triggers hemophagocytic lymphohistiocytosis

Isay S, Vornholz L, Schnalzger T, Groll T, Magg T, Loll P, Weirich G, Steiger K, Hauck F, Ruland J
Proceedings of the National Academy of Sciences 2024;121(51)

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CARD14 signalosome formation is associated with its endosomal relocation and mTORC1-induced keratinocyte proliferation.

O'Sullivan PA, Aidarova A, Afonina IS, Manils J, Thurston TLM, Instrell R, Howell M, Boeing S, Ranawana S, Herpels MB, Chetian R, Bassa M, Flynn H, Frith D, Snijders AP, Howes A, Beyaert R, Bowcock AM, Ley SC
The Biochemical journal 2024 Sep 18;481(18):1143-1171

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HOIL‐1 ubiquitin ligase activity targets unbranched glucosaccharides and is required to prevent polyglucosan accumulation

Kelsall I, McCrory E, Xu Y, Scudamore C, Nanda S, Mancebo‐Gamella P, Wood N, Knebel A, Matthews S, Cohen P
The EMBO Journal 2022;41(8)

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Targeting BCL10 by small peptides for the treatment of B cell lymphoma.

Bao W, Sun C, Sun X, He M, Yu H, Yan W, Wen F, Zhang L, Yang C
Theranostics 2020;10(25):11622-11636

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Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling

Strickson S, Emmerich C, Goh E, Zhang J, Kelsall I, Macartney T, Hastie C, Knebel A, Peggie M, Marchesi F, Arthur J, Cohen P
Proceedings of the National Academy of Sciences 2017;114(17)

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Shigella flexneri suppresses NF-κB activation by inhibiting linear ubiquitin chain ligation

de Jong M, Liu Z, Chen D, Alto N
Nature Microbiology 2016;1(7)

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UBE2L3 Polymorphism Amplifies NF-κB Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases

Lewis M, Vyse S, Shields A, Boeltz S, Gordon P, Spector T, Lehner P, Walczak H, Vyse T
The American Journal of Human Genetics 2015;96(2):221-234

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The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling

Klein T, Fung S, Renner F, Blank M, Dufour A, Kang S, Bolger-Munro M, Scurll J, Priatel J, Schweigler P, Melkko S, Gold M, Viner R, Régnier C, Turvey S, Overall C
Nature Communications 2015;6(1)