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- Antigen structure
- References [19]
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- Product number
- HPA018113 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA018113, RRID:AB_1858421
- Product name
- Anti-TTBK2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TTBK2, Gene description: tau tubulin kinase 2, Alternative Gene Names: KIAA0847, SCA11, Validated applications: WB, IHC, Uniprot ID: Q6IQ55, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references TTBK2 controls cilium stability by regulating distinct modules of centrosomal proteins
Phosphorylation of MIF by PIP4K2a is necessary for cilia biogenesis
Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells–derived neural rosettes
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole
Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ
Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response
Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins
CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells
Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis
Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs
High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome
Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis
Lineage specificity of primary cilia in the mouse embryo
Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole
Nguyen A, Goetz S, Pazour G
Molecular Biology of the Cell 2023;34(1)
Molecular Biology of the Cell 2023;34(1)
Phosphorylation of MIF by PIP4K2a is necessary for cilia biogenesis
Zhang L, Zhang H, Agborbesong E, Zhou J, Li X
Cell Death & Disease 2023;14(12)
Cell Death & Disease 2023;14(12)
Tau tubulin kinase 1 and 2 regulate ciliogenesis and human pluripotent stem cells–derived neural rosettes
Binó L, Čajánek L
Scientific Reports 2023;13(1)
Scientific Reports 2023;13(1)
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis
Kumar D, Hall E, Prosser S, Yeyati P, Herranz-Pérez V, García-Verdugo J, Rose L, McKie L, Dodd D, Tennant P, Megaw R, Murphy L, Ferreira M, Grimes G, Williams L, Quidwai T, Pelletier L, Reiter J, Mill P
eLife 2023;12
eLife 2023;12
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole
Shen X, Yuan J, Qin X, Song G, Hu H, Tu H, Song Z, Li P, Xu Y, Li S, Jian X, Li J, He C, Yu X, Liang L, Wu M, Han Q, Wang K, Li A, Zhou T, Zhang Y, Wang N, Li H
Journal of Cell Biology 2022;221(1)
Journal of Cell Biology 2022;221(1)
Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling
Bernatik O, Paclikova P, Kotrbova A, Bryja V, Cajanek L
Frontiers in Cell and Developmental Biology 2021;9
Frontiers in Cell and Developmental Biology 2021;9
Ciliopathy protein HYLS1 coordinates the biogenesis and signaling of primary cilia by activating the ciliary lipid kinase PIPKIγ
Chen C, Xu Q, Zhang Y, Davies B, Huang Y, Katzmann D, Harris P, Hu J, Ling K
Science Advances 2021;7(26)
Science Advances 2021;7(26)
Genotoxic stress-activated DNA-PK-p53 cascade and autophagy cooperatively induce ciliogenesis to maintain the DNA damage response
Chen T, Huang B, Tang T, Chao Y, Xiao X, Lee P, Yang L, Wang C
Cell Death & Differentiation 2021;28(6):1865-1879
Cell Death & Differentiation 2021;28(6):1865-1879
Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins
Sobu Y, Wawro P, Dhekne H, Yeshaw W, Pfeffer S
Proceedings of the National Academy of Sciences 2021;118(10)
Proceedings of the National Academy of Sciences 2021;118(10)
CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells
Kobayashi T, Tanaka K, Mashima Y, Shoda A, Tokuda M, Itoh H
Frontiers in Cell and Developmental Biology 2020;8
Frontiers in Cell and Developmental Biology 2020;8
Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis
Fan J, You L, Wang W, Huang W, Chu C, Chi Y, Chen H
EMBO reports 2020;21(10)
EMBO reports 2020;21(10)
Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs
Hanáková K, Bernatík O, Kravec M, Micka M, Kumar J, Harnoš J, Ovesná P, Paclíková P, Rádsetoulal M, Potěšil D, Tripsianes K, Čajánek L, Zdráhal Z, Bryja V
Cell Communication and Signaling 2019;17(1)
Cell Communication and Signaling 2019;17(1)
High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy
Bowler M, Kong D, Sun S, Nanjundappa R, Evans L, Farmer V, Holland A, Mahjoub M, Sui H, Loncarek J
Nature Communications 2019;10(1)
Nature Communications 2019;10(1)
Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation.
Lo CH, Lin IH, Yang TT, Huang YC, Tanos BE, Chou PC, Chang CW, Tsay YG, Liao JC, Wang WJ
The Journal of cell biology 2019 Oct 7;218(10):3489-3505
The Journal of cell biology 2019 Oct 7;218(10):3489-3505
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening
Weng R, Yang T, Huang C, Chang C, Wang W, Liao J
Biophysical Journal 2018;115(2):263-275
Biophysical Journal 2018;115(2):263-275
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome
Loukil A, Tormanen K, Sütterlin C
Journal of Cell Biology 2017;216(5):1287-1300
Journal of Cell Biology 2017;216(5):1287-1300
Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K
Nature Communications 2016;7(1)
Nature Communications 2016;7(1)
Lineage specificity of primary cilia in the mouse embryo
Bangs F, Schrode N, Hadjantonakis A, Anderson K
Nature Cell Biology 2015;17(2):113-122
Nature Cell Biology 2015;17(2):113-122
Cep164 triggers ciliogenesis by recruiting Tau tubulin kinase 2 to the mother centriole
Čajánek L, Nigg E
Proceedings of the National Academy of Sciences 2014;111(28)
Proceedings of the National Academy of Sciences 2014;111(28)
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