APR02632G

antibody from Leading Biology
Targeting: NLRP3 AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1
Provider product page for APR02632G
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
APR02632G - Provider product page
Provider
Leading Biology
Product name
NALP3 / NLRP3 Antibody (N-Terminus)
Antibody type
Polyclonal
Description
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
Reactivity
Human
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
NLRP3 protein structure - APR02632G shown in red.