Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- HPA048776 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA048776, RRID:AB_2680518
- Product name
- Anti-MCUB
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MCUB, Gene description: mitochondrial calcium uniporter dominant negative beta subunit, Alternative Gene Names: CCDC109B, FLJ20647, Validated applications: WB, Uniprot ID: Q9NWR8, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Cyclophilin D plays a critical role in the survival of senescent cells.
SGLT2 inhibitor empagliflozin alleviates cardiac remodeling and contractile anomalies in a FUNDC1-dependent manner in experimental Parkinson’s disease
Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft
MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium
Mild Traumatic Brain Injury Induces Mitochondrial Calcium Overload and Triggers the Upregulation of NCLX in the Hippocampus.
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria
Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function
Protasoni M, López-Polo V, Stephan-Otto Attolini C, Brandariz J, Herranz N, Mateo J, Ruiz S, Fernandez-Capetillo O, Kovatcheva M, Serrano M
The EMBO journal 2024 Dec;43(23):5972-6000
The EMBO journal 2024 Dec;43(23):5972-6000
SGLT2 inhibitor empagliflozin alleviates cardiac remodeling and contractile anomalies in a FUNDC1-dependent manner in experimental Parkinson’s disease
Yu W, Wang L, Ren W, Xu H, Wu N, Yu D, Reiter R, Zha W, Guo Q, Ren J
Acta Pharmacologica Sinica 2023;45(1):87-97
Acta Pharmacologica Sinica 2023;45(1):87-97
Rewiring of the 3D genome during acquisition of carboplatin resistance in a triple-negative breast cancer patient-derived xenograft
Dozmorov M, Marshall M, Rashid N, Grible J, Valentine A, Olex A, Murthy K, Chakraborty A, Reyna J, Figueroa D, Hinojosa-Gonzalez L, Da-Inn Lee E, Baur B, Roy S, Ay F, Harrell J
Scientific Reports 2023;13(1)
Scientific Reports 2023;13(1)
MCU Upregulation Overactivates Mitophagy by Promoting VDAC1 Dimerization and Ubiquitination in the Hepatotoxicity of Cadmium
Liu C, Li H, Duan W, Duan Y, Yu Q, Zhang T, Sun Y, Li Y, Liu Y, Xu S
Advanced Science 2023;10(7)
Advanced Science 2023;10(7)
Mild Traumatic Brain Injury Induces Mitochondrial Calcium Overload and Triggers the Upregulation of NCLX in the Hippocampus.
Mira RG, Quintanilla RA, Cerpa W
Antioxidants (Basel, Switzerland) 2023 Feb 7;12(2)
Antioxidants (Basel, Switzerland) 2023 Feb 7;12(2)
Sleep/wake calcium dynamics, respiratory function, and ROS production in cardiac mitochondria
Abdel-Rahman E, Hosseiny S, Aaliya A, Adel M, Yasseen B, Al-Okda A, Radwan Y, Saber S, Elkholy N, Elhanafy E, Walker E, Zuniga-Hertz J, Patel H, Griffiths H, Ali S
Journal of Advanced Research 2021;31
Journal of Advanced Research 2021;31
Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function
Suarez J, Cividini F, Scott B, Lehmann K, Diaz-Juarez J, Diemer T, Dai A, Suarez J, Jain M, Dillmann W
Journal of Biological Chemistry 2018;293(21):8182-8195
Journal of Biological Chemistry 2018;293(21):8182-8195
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