Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 24787-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PHF14 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PHF14 antibody (Cat. #24787-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SP4 Facilitates Esophageal Squamous Cell Carcinoma Progression by Activating PHF14 Transcription and Wnt/Β-Catenin Signaling.
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.
PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.
The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways.
PHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells.
Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.
Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression.
Wei L, Deng C, Zhang B, Wang G, Meng Y, Qin H
Molecular cancer research : MCR 2024 Jan 2;22(1):55-69
Molecular cancer research : MCR 2024 Jan 2;22(1):55-69
KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics.
Mouti MA, Deng S, Pook M, Malzahn J, Rendek A, Militi S, Nibhani R, Soonawalla Z, Oppermann U, Hwang CI, Pauklin S
Nature communications 2023 Sep 14;14(1):5685
Nature communications 2023 Sep 14;14(1):5685
PHF14 enhances DNA methylation of SMAD7 gene to promote TGF-β-driven lung adenocarcinoma metastasis.
Tian H, Liu C, Yu J, Han J, Du J, Liang S, Wang W, Liu Q, Lian R, Zhu T, Wu S, Tao T, Ye Y, Zhao J, Yang Y, Zhu X, Cai J, Wu J, Li M
Cell discovery 2023 Apr 18;9(1):41
Cell discovery 2023 Apr 18;9(1):41
The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways.
Gómez-Marín E, Posavec-Marjanović M, Zarzuela L, Basurto-Cayuela L, Guerrero-Martínez JA, Arribas G, Yerbes R, Ceballos-Chávez M, Rodríguez-Paredes M, Tomé M, Durán RV, Buschbeck M, Reyes JC
Nucleic acids research 2022 Sep 23;50(17):9838-9857
Nucleic acids research 2022 Sep 23;50(17):9838-9857
PHF14 Promotes Cell Proliferation and Migration through the AKT and ERK1/2 Pathways in Gastric Cancer Cells.
Zhao Y, He J, Li Y, Xu M, Peng X, Mao J, Xu B, Cui H
BioMed research international 2020;2020:6507510
BioMed research international 2020;2020:6507510
Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation.
Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Côté J, Trouche D
eLife 2020 Feb 28;9
eLife 2020 Feb 28;9
Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced de novo protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression.
Park JE, Tse SW, Xue G, Assisi C, Maqueda AS, Ramon GPX, Low JK, Kon OL, Tay CY, Tam JP, Sze SK
Oncotarget 2019 Mar 15;10(22):2136-2150
Oncotarget 2019 Mar 15;10(22):2136-2150
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 24787-1-AP( PHF14 Antibody) at dilution of 1:600
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 24787-1-AP( PHF14 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHF14 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PHF14. This antibody recognizes human antigen. The PHF14 antibody has been validated for the following applications: ELISA, WB, IHC analysis.