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Learn24790-1-AP
antibody from Proteintech Group
Targeting: GIGYF2
GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 24790-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- GIGYF2 antibody
- Antibody type
- Polyclonal
- Description
- GIGYF2 antibody (Cat. #24790-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human DHX29 detects nonoptimal codon usage to regulate mRNA stability.
A ribosome-bound pseudoknot in the HCV coding region stimulates viral growth by tuning viral translation.
SARS-CoV-2 Nsp2 recruits GIGYF2 near viral replication sites and supports viral protein production.
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
RNA-binding protein GIGYF2 orchestrates hepatic insulin resistance through STAU1/PTEN-mediated disruption of the PI3K/AKT signaling cascade.
Aberrant hyper-expression of the RNA binding protein GIGYF2 in endothelial cells modulates vascular aging and function.
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression.
BioE3 identifies specific substrates of ubiquitin E3 ligases.
Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress.
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex.
Comparative Proteomic Analysis of tPVAT during Ang II Infusion.
Hia F, Wu Y, Yoshinaga M, Goto-Ito S, Iwasaki W, Imami K, Toh H, Han P, Cai T, Ohira T, Fukao A, Standley DM, Shichino Y, Takegawa M, Fujiwara T, Suzuki T, Iwasaki S, Bassik MC, Ito T, Takeuchi O
Science (New York, N.Y.) 2026 May 7;392(6798):eadw0288
Science (New York, N.Y.) 2026 May 7;392(6798):eadw0288
A ribosome-bound pseudoknot in the HCV coding region stimulates viral growth by tuning viral translation.
Wan H, Jang H, Xu L, Abdallah KS, Gilbert WV, Pyle AM
Cell reports 2026 Jan 27;45(1):116739
Cell reports 2026 Jan 27;45(1):116739
SARS-CoV-2 Nsp2 recruits GIGYF2 near viral replication sites and supports viral protein production.
Kim J, Park Y, Yoon D, Lee S, Kim H, Ban KY, Yang J, Choi DE, Kim J, Kim JS, Kim VN
Nucleic acids research 2025 Jul 19;53(14)
Nucleic acids research 2025 Jul 19;53(14)
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
Chatterjee S, Naeli P, Onar O, Simms N, Garzia A, Hackett A, Coyle K, Harris Snell P, McGirr T, Sawant TN, Dang K, Stoichkova ZV, Azam Y, Saunders MP, Braun M, Alain T, Tuschl T, McDade SS, Longley DB, Gkogkas CG, Adrain C, Knight JRP, Jafarnejad SM
Nucleic acids research 2024 Nov 11;52(20):12534-12548
Nucleic acids research 2024 Nov 11;52(20):12534-12548
Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.
Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B
Nature communications 2024 Feb 22;15(1):1637
Nature communications 2024 Feb 22;15(1):1637
RNA-binding protein GIGYF2 orchestrates hepatic insulin resistance through STAU1/PTEN-mediated disruption of the PI3K/AKT signaling cascade.
Lv Z, Ren Y, Li Y, Niu F, Li Z, Li M, Li X, Li Q, Huang D, Yu Y, Xiong Y, Qian L
Molecular medicine (Cambridge, Mass.) 2024 Aug 13;30(1):124
Molecular medicine (Cambridge, Mass.) 2024 Aug 13;30(1):124
Aberrant hyper-expression of the RNA binding protein GIGYF2 in endothelial cells modulates vascular aging and function.
Niu F, Li Z, Ren Y, Li Z, Guan H, Li Y, Zhang Y, Li Y, Yang J, Qian L, Shi W, Fan X, Li J, Shi L, Yu Y, Xiong Y
Redox biology 2023 Sep;65:102824
Redox biology 2023 Sep;65:102824
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation.
Wang H, Cui X, Wang L, Fan N, Yu M, Qin H, Liu S, Yan Q
Cell death & disease 2023 Oct 6;14(10):651
Cell death & disease 2023 Oct 6;14(10):651
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression.
Naeli P, Zhang X, Snell PH, Chatterjee S, Kamran M, Ladak RJ, Orr N, Duchaine T, Sonenberg N, Jafarnejad SM
Journal of cell science 2023 Oct 1;136(19)
Journal of cell science 2023 Oct 1;136(19)
BioE3 identifies specific substrates of ubiquitin E3 ligases.
Barroso-Gomila O, Merino-Cacho L, Muratore V, Perez C, Taibi V, Maspero E, Azkargorta M, Iloro I, Trulsson F, Vertegaal ACO, Mayor U, Elortza F, Polo S, Barrio R, Sutherland JD
Nature communications 2023 Nov 23;14(1):7656
Nature communications 2023 Nov 23;14(1):7656
Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress.
Lehner MH, Walker J, Temcinaite K, Herlihy A, Taschner M, Berger AC, Corbett AH, Dirac Svejstrup AB, Svejstrup JQ
Cell reports 2022 Oct 25;41(4):111536
Cell reports 2022 Oct 25;41(4):111536
The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex.
Zou L, Moch C, Graille M, Chapat C
iScience 2022 Jul 15;25(7):104646
iScience 2022 Jul 15;25(7):104646
Comparative Proteomic Analysis of tPVAT during Ang II Infusion.
Liang X, Guan H, Sun J, Qi Y, Yao W
Biomedicines 2021 Dec 2;9(12)
Biomedicines 2021 Dec 2;9(12)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GIGYF2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human GIGYF2. This antibody recognizes human antigen. The GIGYF2 antibody has been validated for the following applications: ELISA, WB analysis.
