12289-1-AP
antibody from Proteintech Group
Targeting: CLU
APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2
Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 12289-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12289-1-AP, RRID:AB_2083316
- Product name
- Clusterin antibody
- Antibody type
- Polyclonal
- Description
- Clusterin antibody (Cat. #12289-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues.
The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation.
Proteomics analysis of lung tissue reveals protein makers for the lung injury of adjuvant arthritis rats.
NRG1 Regulates Proliferation, Migration and Differentiation of Human Limbal Epithelial Stem Cells.
Identification of hub genes and pathways in lung metastatic colorectal cancer.
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers.
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway.
N-linked glycoproteomic profiling in esophageal squamous cell carcinoma.
N(6)-adenomethylation of GsdmC is essential for Lgr5(+) stem cell survival to maintain normal colonic epithelial morphogenesis.
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes.
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Clusterin overexpression as a potential neuroprotective response to the pathological effects of high fat dieting on the brain reward system.
Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.
Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole.
Salidroside-Mitigated Inflammatory Injury of Hepatocytes with Non-Alcoholic Fatty Liver Disease via Inhibition TRPM2 Ion Channel Activation.
Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway.
Proteomic analysis of rat serum revealed the effects of chronic sleep deprivation on metabolic, cardiovascular and nervous system.
Bathing in carbon dioxide-enriched water alters protein expression in keratinocytes of skin tissue in rats.
Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release.
Wu J, Wang C, Sun S, Ren T, Pan L, Liu H, Hou S, Wu S, Yan X, Zhang J, Zhao X, Liu W, Zhu S, Wei S, Zhang C, Jia X, Zhang Q, Yu Z, Zhuo Y, Zhao Q, Yang C, Wang N
Protein & cell 2024 Jul 20;15(8):594-611
Protein & cell 2024 Jul 20;15(8):594-611
The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation.
Li M, Guo H, Wang B, Han Z, Wu S, Liu J, Huang H, Zhu J, An F, Lin Z, Mo K, Tan J, Liu C, Wang L, Deng X, Li G, Ji J, Ouyang H
Nature communications 2024 Jan 4;15(1):256
Nature communications 2024 Jan 4;15(1):256
Proteomics analysis of lung tissue reveals protein makers for the lung injury of adjuvant arthritis rats.
Zhang PH, Wu DB, Liu J, Wen JT, Chen ES, Xiao CH
Molecular medicine reports 2023 Sep;28(3)
Molecular medicine reports 2023 Sep;28(3)
NRG1 Regulates Proliferation, Migration and Differentiation of Human Limbal Epithelial Stem Cells.
Wang B, Guo H, Han Z, Wu S, Liu J, Lin Z, An F, Zhu J, Li M
Current issues in molecular biology 2023 Dec 14;45(12):10121-10130
Current issues in molecular biology 2023 Dec 14;45(12):10121-10130
Identification of hub genes and pathways in lung metastatic colorectal cancer.
Dai W, Guo C, Wang Y, Li Y, Xie R, Wu J, Yao B, Xie D, He L, Li Y, Huang H, Wang Y, Liu S
BMC cancer 2023 Apr 6;23(1):323
BMC cancer 2023 Apr 6;23(1):323
PINK1-Dependent Mitophagy Reduced Endothelial Hyperpermeability and Cell Migration Capacity Under Simulated Microgravity.
Li C, Pan Y, Tan Y, Wang Y, Sun X
Frontiers in cell and developmental biology 2022;10:896014
Frontiers in cell and developmental biology 2022;10:896014
Serum exosomal proteomics analysis of lung adenocarcinoma to discover new tumor markers.
Liu S, Tian W, Ma Y, Li J, Yang J, Li B
BMC cancer 2022 Mar 15;22(1):279
BMC cancer 2022 Mar 15;22(1):279
Clusterin protects against Cr(VI)-induced oxidative stress-associated hepatotoxicity by mediating the Akt-Keap1-Nrf2 signaling pathway.
Ma Y, Li S, Tang S, Ye S, Liang N, Liang Y, Xiao F
Environmental science and pollution research international 2022 Jul;29(34):52289-52301
Environmental science and pollution research international 2022 Jul;29(34):52289-52301
N-linked glycoproteomic profiling in esophageal squamous cell carcinoma.
Liu QW, Ruan HJ, Chao WX, Li MX, Jiao YL, Ward DG, Gao SG, Qi YJ
World journal of gastroenterology 2022 Aug 7;28(29):3869-3885
World journal of gastroenterology 2022 Aug 7;28(29):3869-3885
N(6)-adenomethylation of GsdmC is essential for Lgr5(+) stem cell survival to maintain normal colonic epithelial morphogenesis.
Du J, Sarkar R, Li Y, He L, Kang W, Liao W, Liu W, Nguyen T, Zhang L, Deng Z, Dougherty U, Kupfer SS, Chen M, Pekow J, Bissonnette M, He C, Li YC
Developmental cell 2022 Aug 22;57(16):1976-1994.e8
Developmental cell 2022 Aug 22;57(16):1976-1994.e8
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes.
Li X, Chen R, Kemper S, Brigstock DR
Frontiers in cell and developmental biology 2021;9:640667
Frontiers in cell and developmental biology 2021;9:640667
Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium.
Ma Y, Liang Y, Liang N, Zhang Y, Xiao F
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Ecotoxicology and environmental safety 2021 Mar 15;211:111908
Clusterin overexpression as a potential neuroprotective response to the pathological effects of high fat dieting on the brain reward system.
Rodríguez-Rivera C, Pérez-Ortiz JM, Pook E, Conjaerts N, Alguacil LF, González-Martín C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jun;152:112186
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Jun;152:112186
Addiction to Golgi-resident PI4P synthesis in chromosome 1q21.3-amplified lung adenocarcinoma cells.
Shi L, Tan X, Liu X, Yu J, Bota-Rabassedas N, Niu Y, Luo J, Xi Y, Zong C, Creighton CJ, Glenn JS, Wang J, Kurie JM
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 22;118(25)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jun 22;118(25)
Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole.
Udawatte NS, Kang SW, Wang Y, Arumugam TV, Seneviratne CJ
Frontiers in pharmacology 2020;11:511
Frontiers in pharmacology 2020;11:511
Salidroside-Mitigated Inflammatory Injury of Hepatocytes with Non-Alcoholic Fatty Liver Disease via Inhibition TRPM2 Ion Channel Activation.
Feng Q, Liu C, Gao W, Geng XL, Dai N
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2755-2763
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:2755-2763
Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway.
Zhang Y, Zhang Y, Xiao Y, Zhong C, Xiao F
Ecotoxicology and environmental safety 2019 Nov 15;183:109465
Ecotoxicology and environmental safety 2019 Nov 15;183:109465
Proteomic analysis of rat serum revealed the effects of chronic sleep deprivation on metabolic, cardiovascular and nervous system.
Ma B, Chen J, Mu Y, Xue B, Zhao A, Wang D, Chang D, Pan Y, Liu J
PloS one 2018;13(9):e0199237
PloS one 2018;13(9):e0199237
Bathing in carbon dioxide-enriched water alters protein expression in keratinocytes of skin tissue in rats.
Kälsch J, Pott LL, Takeda A, Kumamoto H, Möllmann D, Canbay A, Sitek B, Baba HA
International journal of biometeorology 2017 Apr;61(4):739-746
International journal of biometeorology 2017 Apr;61(4):739-746
Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release.
Donner L, Fälker K, Gremer L, Klinker S, Pagani G, Ljungberg LU, Lothmann K, Rizzi F, Schaller M, Gohlke H, Willbold D, Grenegard M, Elvers M
Science signaling 2016 May 24;9(429):ra52
Science signaling 2016 May 24;9(429):ra52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 12289-1-AP(CLU antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Clusterin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Clusterin. This antibody recognizes human,mouse,rat antigen. The Clusterin antibody has been validated for the following applications: ELISA, WB, IHC analysis.