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- References [19]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 10586-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10586-1-AP, RRID:AB_2197283
- Product name
- STMN2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STMN2 antibody (Cat. #10586-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Eml1 promotes axonal growth by enhancing αTAT1-mediated microtubule acetylation.
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.
Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP.
Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons.
Atg7 Knockout Alleviated the Axonal Injury of Neuro-2a Cells Induced by Tri-Ortho-Cresyl Phosphate.
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10.
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.
Retrograde Ret signaling controls sensory pioneer axon outgrowth.
Key role of SMN/SYNCRIP and RNA-Motif 7 in spinal muscular atrophy: RNA-Seq and motif analysis of human motor neurons.
A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.
Kif1B Interacts with KBP to Promote Axon Elongation by Localizing a Microtubule Regulator to Growth Cones.
Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells.
Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia.
Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity.
Modulation of central nervous system-specific microRNA-124a alters the inflammatory response in the formalin test in mice.
SCG10 is a JNK target in the axonal degeneration pathway.
CNGA3: a target of spinal nitric oxide/cGMP signaling and modulator of inflammatory pain hypersensitivity.
Interleukin-6 and neural stem cells: more than gliogenesis.
Zhang Y, Guan T, Li Z, Guo B, Luo X, Guo L, Li M, Xu M, Liu M, Liu Y
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119770
Biochimica et biophysica acta. Molecular cell research 2024 Oct;1871(7):119770
A model of human neural networks reveals NPTX2 pathology in ALS and FTLD.
Hruska-Plochan M, Wiersma VI, Betz KM, Mallona I, Ronchi S, Maniecka Z, Hock EM, Tantardini E, Laferriere F, Sahadevan S, Hoop V, Delvendahl I, Pérez-Berlanga M, Gatta B, Panatta M, van der Bourg A, Bohaciakova D, Sharma P, De Vos L, Frontzek K, Aguzzi A, Lashley T, Robinson MD, Karayannis T, Mueller M, Hierlemann A, Polymenidou M
Nature 2024 Feb;626(8001):1073-1083
Nature 2024 Feb;626(8001):1073-1083
Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP.
Cooper-Knock J, Julian TH, Feneberg E, Highley JR, Sidra M, Turner MR, Talbot K, Ansorge O, Allen SP, Moll T, Shelkovnikova T, Castelli L, Hautbergue GM, Hewitt C, Kirby J, Wharton SB, Mead RJ, Shaw PJ
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13104
Brain pathology (Zurich, Switzerland) 2023 Jan;33(1):e13104
Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons.
Alexandris AS, Ryu J, Rajbhandari L, Harlan R, McKenney J, Wang Y, Aja S, Graham D, Venkatesan A, Koliatsos VE
Neurobiology of disease 2022 Sep;171:105808
Neurobiology of disease 2022 Sep;171:105808
Atg7 Knockout Alleviated the Axonal Injury of Neuro-2a Cells Induced by Tri-Ortho-Cresyl Phosphate.
Zhang C, Kang K, Chen Y, Shan S, Xie K, Song F
Neurotoxicity research 2021 Aug;39(4):1076-1086
Neurotoxicity research 2021 Aug;39(4):1076-1086
Immunohistochemical validation study of 15-gene biomarker panel predictive of benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of JBR.10.
Grieve S, Ding K, Moore J, Finniss M, Ray A, Lees M, Hossain F, Murugesan A, Agar J, Acar C, Taylor J, Shepherd FA, Reiman T
ESMO open 2020 Mar;5(2)
ESMO open 2020 Mar;5(2)
Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.
Loreto A, Hill CS, Hewitt VL, Orsomando G, Angeletti C, Gilley J, Lucci C, Sanchez-Martinez A, Whitworth AJ, Conforti L, Dajas-Bailador F, Coleman MP
Neurobiology of disease 2020 Feb;134:104678
Neurobiology of disease 2020 Feb;134:104678
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.
Ko KW, Milbrandt J, DiAntonio A
The Journal of cell biology 2020 Aug 3;219(8)
The Journal of cell biology 2020 Aug 3;219(8)
Retrograde Ret signaling controls sensory pioneer axon outgrowth.
Tuttle A, Drerup CM, Marra M, McGraw H, Nechiporuk AV
eLife 2019 Sep 2;8
eLife 2019 Sep 2;8
Key role of SMN/SYNCRIP and RNA-Motif 7 in spinal muscular atrophy: RNA-Seq and motif analysis of human motor neurons.
Rizzo F, Nizzardo M, Vashisht S, Molteni E, Melzi V, Taiana M, Salani S, Santonicola P, Di Schiavi E, Bucchia M, Bordoni A, Faravelli I, Bresolin N, Comi GP, Pozzoli U, Corti S
Brain : a journal of neurology 2019 Feb 1;142(2):276-294
Brain : a journal of neurology 2019 Feb 1;142(2):276-294
A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.
Feinberg K, Kolaj A, Wu C, Grinshtein N, Krieger JR, Moran MF, Rubin LL, Miller FD, Kaplan DR
The Journal of cell biology 2017 Nov 6;216(11):3655-3675
The Journal of cell biology 2017 Nov 6;216(11):3655-3675
Kif1B Interacts with KBP to Promote Axon Elongation by Localizing a Microtubule Regulator to Growth Cones.
Drerup CM, Lusk S, Nechiporuk A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jun 29;36(26):7014-26
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Jun 29;36(26):7014-26
Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells.
Kalwat MA, Huang Z, Wichaidit C, McGlynn K, Earnest S, Savoia C, Dioum EM, Schneider JW, Hutchison MR, Cobb MH
ACS chemical biology 2016 Apr 15;11(4):1128-36
ACS chemical biology 2016 Apr 15;11(4):1128-36
Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia.
Mukai J, Tamura M, Fénelon K, Rosen AM, Spellman TJ, Kang R, MacDermott AB, Karayiorgou M, Gordon JA, Gogos JA
Neuron 2015 May 6;86(3):680-95
Neuron 2015 May 6;86(3):680-95
Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity.
Kallenborn-Gerhardt W, Hohmann SW, Syhr KM, Schröder K, Sisignano M, Weigert A, Lorenz JE, Lu R, Brüne B, Brandes RP, Geisslinger G, Schmidtko A
Pain 2014 Oct;155(10):2161-70
Pain 2014 Oct;155(10):2161-70
Modulation of central nervous system-specific microRNA-124a alters the inflammatory response in the formalin test in mice.
Kynast KL, Russe OQ, Möser CV, Geisslinger G, Niederberger E
Pain 2013 Mar;154(3):368-376
Pain 2013 Mar;154(3):368-376
SCG10 is a JNK target in the axonal degeneration pathway.
Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayum S, Russler EV, Cavalli V, Milbrandt J, DiAntonio A
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 26;109(52):E3696-705
Proceedings of the National Academy of Sciences of the United States of America 2012 Dec 26;109(52):E3696-705
CNGA3: a target of spinal nitric oxide/cGMP signaling and modulator of inflammatory pain hypersensitivity.
Heine S, Michalakis S, Kallenborn-Gerhardt W, Lu R, Lim HY, Weiland J, Del Turco D, Deller T, Tegeder I, Biel M, Geisslinger G, Schmidtko A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 3;31(31):11184-92
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 Aug 3;31(31):11184-92
Interleukin-6 and neural stem cells: more than gliogenesis.
Islam O, Gong X, Rose-John S, Heese K
Molecular biology of the cell 2009 Jan;20(1):188-99
Molecular biology of the cell 2009 Jan;20(1):188-99
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 10586-1-AP(STMN2 antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-STMN2 (IP:10586-1-AP, 3ug; Detection:10586-1-AP 1:1000) with mouse brain tissue lysate 9500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STMN2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STMN2. This antibody recognizes human,mouse,rat antigen. The STMN2 antibody has been validated for the following applications: ELISA, IHC, IP, WB analysis.
