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- References [9]
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- Western blot [1]
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- Product number
- 23992-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- TMEM55B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TMEM55B antibody (Cat. #23992-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Control of lysosome function by the GTPase-activating protein TBC1D9B and its binding partner TMEM55B.
Novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease.
TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress.
Longitudinal autophagy profiling of the mammalian brain reveals sustained mitophagy throughout healthy aging.
TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney.
Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites.
Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation.
Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation.
TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.
Duhay V, Tian M, Kosieradzka K, Ebner M, Lo WT, Krauss M, Sprengel HL, Voss M, Riechmann M, Savas JN, Schwake M, Haucke V, Damme M
Nature communications 2026 Mar 14;17(1)
Nature communications 2026 Mar 14;17(1)
Novel autophagy inducers by accelerating lysosomal clustering against Parkinson's disease.
Date Y, Sasazawa Y, Kitagawa M, Gejima K, Suzuki A, Saya H, Kida Y, Imoto M, Itakura E, Hattori N, Saiki S
eLife 2024 Jul 3;13
eLife 2024 Jul 3;13
TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress.
Jeong E, Willett R, Rissone A, La Spina M, Puertollano R
Nature communications 2024 Jan 2;15(1):93
Nature communications 2024 Jan 2;15(1):93
Longitudinal autophagy profiling of the mammalian brain reveals sustained mitophagy throughout healthy aging.
Rappe A, Vihinen HA, Suomi F, Hassinen AJ, Ehsan H, Jokitalo ES, McWilliams TG
The EMBO journal 2024 Dec;43(23):6199-6231
The EMBO journal 2024 Dec;43(23):6199-6231
TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney.
Nakamura J, Yamamoto T, Takabatake Y, Namba-Hamano T, Minami S, Takahashi A, Matsuda J, Sakai S, Yonishi H, Maeda S, Matsui S, Matsui I, Hamano T, Takahashi M, Goto M, Izumi Y, Bamba T, Sasai M, Yamamoto M, Matsusaka T, Niimura F, Yanagita M, Nakamura S, Yoshimori T, Ballabio A, Isaka Y
JCI insight 2023 Feb 22;8(4)
JCI insight 2023 Feb 22;8(4)
Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites.
Du Y, Chang W, Gao L, Deng L, Ji WK
The Journal of cell biology 2023 Apr 3;222(4)
The Journal of cell biology 2023 Apr 3;222(4)
Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation.
Shirane M, Wada M, Morita K, Hayashi N, Kunimatsu R, Matsumoto Y, Matsuzaki F, Nakatsumi H, Ohta K, Tamura Y, Nakayama KI
Nature communications 2020 Sep 11;11(1):4576
Nature communications 2020 Sep 11;11(1):4576
Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation.
Qin Y, Ting F, Kim MJ, Strelnikov J, Harmon J, Gao F, Dose A, Teng BB, Alipour MA, Yao Z, Crooke R, Krauss RM, Medina MW
Arteriosclerosis, thrombosis, and vascular biology 2020 May;40(5):1311-1324
Arteriosclerosis, thrombosis, and vascular biology 2020 May;40(5):1311-1324
TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.
Hashimoto Y, Shirane M, Nakayama KI
Genes to cells : devoted to molecular & cellular mechanisms 2018 Jun;23(6):418-434
Genes to cells : devoted to molecular & cellular mechanisms 2018 Jun;23(6):418-434
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 23992-1-AP( TMEM55B Antibody) at dilution of 1:300
- Other comments
- WB
