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antibody from antibodies-online
Targeting: SCN5A
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN350855 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350855, RRID:AB_10787614
- Product name
- anti-Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A) (Internal Region) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the internal region of human Sodium channel protein type 5 subunit alpha (SCN5A, Nav1.5) conjugated to an immunogenic carrier protein was used as the antigen.
- Description
- Whole serum
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- Internal Region
- Vial size
- 100 μL
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.
Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination.
A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels.
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome.
Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel.
Ou SW, Kameyama A, Hao LY, Horiuchi M, Minobe E, Wang WY, Makita N, Kameyama M
The European journal of neuroscience 2005 Aug;22(4):793-801
The European journal of neuroscience 2005 Aug;22(4):793-801
Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination.
van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H
Circulation research 2004 Aug 6;95(3):284-91
Circulation research 2004 Aug 6;95(3):284-91
A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels.
Makielski JC, Ye B, Valdivia CR, Pagel MD, Pu J, Tester DJ, Ackerman MJ
Circulation research 2003 Oct 31;93(9):821-8
Circulation research 2003 Oct 31;93(9):821-8
Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome.
Vatta M, Dumaine R, Varghese G, Richard TA, Shimizu W, Aihara N, Nademanee K, Brugada R, Brugada J, Veerakul G, Li H, Bowles NE, Brugada P, Antzelevitch C, Towbin JA
Human molecular genetics 2002 Feb 1;11(3):337-45
Human molecular genetics 2002 Feb 1;11(3):337-45
Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel.
Gellens ME, George AL Jr, Chen LQ, Chahine M, Horn R, Barchi RL, Kallen RG
Proceedings of the National Academy of Sciences of the United States of America 1992 Jan 15;89(2):554-8
Proceedings of the National Academy of Sciences of the United States of America 1992 Jan 15;89(2):554-8
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