23016-1-AP

antibody from Proteintech Group

Targeting: SCN5A CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

23016-1-AP

Provider

Proteintech Group

Product name

Nav1.5 antibody

Antibody type

Polyclonal

Description

Nav1.5 antibody (Cat. #23016-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signals.

Wang J, Liu Q, Zhou Y, Cao C, Chen P, Meng G, Zhang J, Xin X, Huang G, Wu Y
iScience 2024 Jan 19;27(1):108723

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HAND factors regulate cardiac lineage commitment and differentiation from human pluripotent stem cells.

Guo H, Hang C, Lin B, Lin Z, Xiong H, Zhang M, Lu R, Liu J, Shi D, Xie D, Liu Y, Liang D, Yang J, Chen YH
Stem cell research & therapy 2024 Feb 5;15(1):31

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Sialyltransferase ST3GAL4 confers osimertinib resistance and offers strategies to overcome resistance in non-small cell lung cancer.

Han R, Lin C, Lu C, Wang Y, Kang J, Hu C, Dou Y, Wu D, He T, Tang H, Zheng J, Li L, He Y
Cancer letters 2024 Apr 28;588:216762

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Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels.

Wu W, Yin Y, Feng P, Chen G, Pan L, Gu P, Zhou S, Lin F, Ji S, Zheng C, Deng M
Frontiers in pharmacology 2023;14:1067665

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Alterations in Calcium Handling Are a Common Feature in an Arrhythmogenic Cardiomyopathy Cell Model Triggered by Desmosome Genes Loss.

Vallverdú-Prats M, Carreras D, Pérez GJ, Campuzano O, Brugada R, Alcalde M
International journal of molecular sciences 2023 Jan 20;24(3)

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Mice lacking MBNL1 and MBNL2 exhibit sudden cardiac death and molecular signatures recapitulating myotonic dystrophy.

Lee KY, Seah C, Li C, Chen YF, Chen CY, Wu CI, Liao PC, Shyu YC, Olafson HR, McKee KK, Wang ET, Yeh CH, Wang CH
Human molecular genetics 2022 Sep 10;31(18):3144-3160

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Moricizine prevents atrial fibrillation by late sodium current inhibition in atrial myocytes.

Zou T, Chen Q, Chen C, Liu G, Ling Y, Pang Y, Xu Y, Cheng K, Zhu W, Wang RX, Qian LL, Ge J
Journal of thoracic disease 2022 Jun;14(6):2187-2200

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Changes in ion channel expression and function associated with cardiac arrhythmogenic remodeling by Sorbs2.

Qian LL, Sun X, Yang J, Wang XL, Ackerman MJ, Wang RX, Xu X, Lee HC, Lu T
Biochimica et biophysica acta. Molecular basis of disease 2021 Dec 1;1867(12):166247

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Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.

Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21

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Mechanistic insights into the interaction of the MOG1 protein with the cardiac sodium channel Na(v)1.5 clarify the molecular basis of Brugada syndrome.

Yu G, Liu Y, Qin J, Wang Z, Hu Y, Wang F, Li Y, Chakrabarti S, Chen Q, Wang QK
The Journal of biological chemistry 2018 Nov 23;293(47):18207-18217