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- Antibody Data
- Antigen structure
- References [36]
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- Product number
- 26723-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ATP8 antibody
- Antibody type
- Polyclonal
- Description
- ATP8 antibody (Cat. #26723-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Deafness-associated tRNA(Phe) mutation impaired mitochondrial and cellular integrity.
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels.
Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function.
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis.
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency.
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Mechanistic insights into mitochondrial tRNA(Ala) 3'-end metabolism deficiency.
ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Tissue-specific expression atlas of murine mitochondrial tRNAs.
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNA(His) mutation.
SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
A deafness-associated mitochondrial DNA mutation altered the tRNA(Ser(UCN)) metabolism and mitochondrial function.
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Contribution of the tRNA(Ile) 4317A→G mutation to the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA 1555A→G mutation.
A hypertension-associated mitochondrial DNA mutation introduces an m(1)G37 modification into tRNA(Met), altering its structure and function.
Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.
A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNA(Leu(UUR)).
Chen X, Meng F, Chen C, Li S, Chou Z, Xu B, Mo JQ, Guo Y, Guan MX
The Journal of biological chemistry 2024 May;300(5):107235
The Journal of biological chemistry 2024 May;300(5):107235
Aging-induced tRNA(Glu)-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization.
Li D, Gao X, Ma X, Wang M, Cheng C, Xue T, Gao F, Shen Y, Zhang J, Liu Q
Cell metabolism 2024 May 7;36(5):1059-1075.e9
Cell metabolism 2024 May 7;36(5):1059-1075.e9
MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels.
Tábara LC, Burr SP, Frison M, Chowdhury SR, Paupe V, Nie Y, Johnson M, Villar-Azpillaga J, Viegas F, Segawa M, Anand H, Petkevicius K, Chinnery PF, Prudent J
Cell 2024 Jul 11;187(14):3619-3637.e27
Cell 2024 Jul 11;187(14):3619-3637.e27
Structural insights into the specific recognition of mitochondrial ribosome-binding factor hsRBFA and 12 S rRNA by methyltransferase METTL15.
Lv M, Zhou W, Hao Y, Li F, Zhang H, Yao X, Shi Y, Zhang L
Cell discovery 2024 Jan 30;10(1):11
Cell discovery 2024 Jan 30;10(1):11
Time-resolved proteomic analyses of senescence highlight metabolic rewiring of mitochondria.
Kim JY, Atanassov I, Dethloff F, Kroczek L, Langer T
Life science alliance 2023 Sep;6(9)
Life science alliance 2023 Sep;6(9)
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Shelton SD, House S, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P
bioRxiv : the preprint server for biology 2023 Sep 5;
bioRxiv : the preprint server for biology 2023 Sep 5;
Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function.
Huang M, Coral D, Ardalani H, Spegel P, Saadat A, Claussnitzer M, Mulder H, Franks PW, Kalamajski S
eLife 2023 Mar 6;12
eLife 2023 Mar 6;12
Albumosomes formed by cytoplasmic pre-folding albumin maintain mitochondrial homeostasis and inhibit nonalcoholic fatty liver disease.
Ma B, Ju A, Zhang S, An Q, Xu S, Liu J, Yu L, Fu Y, Luo Y
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Signal transduction and targeted therapy 2023 Jun 16;8(1):229
Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Qin W, Cheah JS, Xu C, Messing J, Freibaum BD, Boeynaems S, Taylor JP, Udeshi ND, Carr SA, Ting AY
Cell 2023 Jul 20;186(15):3307-3324.e30
Cell 2023 Jul 20;186(15):3307-3324.e30
Dynamic mapping of proteome trafficking within and between living cells by TransitID.
Xu WQ, Cheah JS, Xu C, Messing J, Freibaum BD, Boeynaems S, Taylor JP, Udeshi ND, Carr SA, Ting AY
bioRxiv : the preprint server for biology 2023 Feb 8;
bioRxiv : the preprint server for biology 2023 Feb 8;
Novel ELAC2 Mutations in Individuals Presenting with Variably Severe Neurological Disease in the Presence or Absence of Cardiomyopathy.
Cafournet C, Zanin S, Guimier A, Hully M, Assouline Z, Barcia G, de Lonlay P, Steffann J, Munnich A, Bonnefont JP, Rötig A, Ruzzenente B, Metodiev MD
Life (Basel, Switzerland) 2023 Feb 4;13(2)
Life (Basel, Switzerland) 2023 Feb 4;13(2)
A Missense Variant in AIFM1 Caused Mitochondrial Dysfunction and Intolerance to Riboflavin Deficiency.
Zhao Y, Lin Y, Wang B, Liu F, Zhao D, Wang W, Ren H, Wang J, Xu Z, Yan C, Ji K
Neuromolecular medicine 2023 Dec;25(4):489-500
Neuromolecular medicine 2023 Dec;25(4):489-500
MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis.
Ding Y, Gui X, Chu X, Sun Y, Zhang S, Tong H, Ju W, Li Y, Sun Z, Xu M, Li Z, Andrews RK, Gardiner EE, Zeng L, Xu K, Qiao J
Nature communications 2023 Aug 10;14(1):4829
Nature communications 2023 Aug 10;14(1):4829
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Jia Z, Meng F, Chen H, Zhu G, Li X, He Y, Zhang L, He X, Zhan H, Chen M, Ji Y, Wang M, Guan MX
Nucleic acids research 2022 Sep 9;50(16):9368-9381
Nucleic acids research 2022 Sep 9;50(16):9368-9381
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550
The EMBO journal 2022 Dec 1;41(23):e111550
ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.
Yang Y, Li C, Gu X, Zhen J, Zhu S, Lv T, Wan Q, Liu Y
Frontiers in cell and developmental biology 2021;9:700195
Frontiers in cell and developmental biology 2021;9:700195
A Mitochondrial DNA Variant Elevates the Risk of Gallstone Disease by Altering Mitochondrial Function.
Sun D, Niu Z, Zheng HX, Wu F, Jiang L, Han TQ, Wei Y, Wang J, Jin L
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Cellular and molecular gastroenterology and hepatology 2021;11(4):1211-1226.e15
Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency.
Zhang Q, He X, Yao S, Lin T, Zhang L, Chen D, Chen C, Yang Q, Li F, Zhu YM, Guan MX
Nucleic acids research 2021 May 7;49(8):4689-4704
Nucleic acids research 2021 May 7;49(8):4689-4704
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)
The Journal of cell biology 2021 Jun 7;220(6)
Mechanistic insights into mitochondrial tRNA(Ala) 3'-end metabolism deficiency.
Ji Y, Nie Z, Meng F, Hu C, Chen H, Jin L, Chen M, Zhang M, Zhang J, Liang M, Wang M, Guan MX
The Journal of biological chemistry 2021 Jul;297(1):100816
The Journal of biological chemistry 2021 Jul;297(1):100816
ALKBH7-mediated demethylation regulates mitochondrial polycistronic RNA processing.
Zhang LS, Xiong QP, Peña Perez S, Liu C, Wei J, Le C, Zhang L, Harada BT, Dai Q, Feng X, Hao Z, Wang Y, Dong X, Hu L, Wang ED, Pan T, Klungland A, Liu RJ, He C
Nature cell biology 2021 Jul;23(7):684-691
Nature cell biology 2021 Jul;23(7):684-691
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
Jin X, Zhang Z, Nie Z, Wang C, Meng F, Yi Q, Chen M, Sun J, Zou J, Jiang P, Guan MX
The Journal of biological chemistry 2021 Jan-Jun;296:100437
The Journal of biological chemistry 2021 Jan-Jun;296:100437
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Meng F, Zhou M, Xiao Y, Mao X, Zheng J, Lin J, Lin T, Ye Z, Cang X, Fu Y, Wang M, Guan MX
Nucleic acids research 2021 Jan 25;49(2):1075-1093
Nucleic acids research 2021 Jan 25;49(2):1075-1093
Tissue-specific expression atlas of murine mitochondrial tRNAs.
He Q, He X, Xiao Y, Zhao Q, Ye Z, Cui L, Chen Y, Guan MX
The Journal of biological chemistry 2021 Aug;297(2):100960
The Journal of biological chemistry 2021 Aug;297(2):100960
Mitochondrial miR-181a-5p promotes glucose metabolism reprogramming in liver cancer by regulating the electron transport chain.
Zhuang X, Chen Y, Wu Z, Xu Q, Chen M, Shao M, Cao X, Zhou Y, Xie M, Shi Y, Zeng Y, Bu H
Carcinogenesis 2020 Jul 14;41(7):972-983
Carcinogenesis 2020 Jul 14;41(7):972-983
Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNA(His) mutation.
Gong S, Wang X, Meng F, Cui L, Yi Q, Zhao Q, Cang X, Cai Z, Mo JQ, Liang Y, Guan MX
The Journal of biological chemistry 2020 Jan 24;295(4):940-954
The Journal of biological chemistry 2020 Jan 24;295(4):940-954
SQSTM1/p62 Controls mtDNA Expression and Participates in Mitochondrial Energetic Adaption via MRPL12.
Ma Y, Zhu S, Lv T, Gu X, Feng H, Zhen J, Xin W, Wan Q
iScience 2020 Aug 21;23(8):101428
iScience 2020 Aug 21;23(8):101428
Hypertension-associated mitochondrial DNA 4401A>G mutation caused the aberrant processing of tRNAMet, all 8 tRNAs and ND6 mRNA in the light-strand transcript.
Zhao X, Cui L, Xiao Y, Mao Q, Aishanjiang M, Kong W, Liu Y, Chen H, Hong F, Jia Z, Wang M, Jiang P, Guan MX
Nucleic acids research 2019 Nov 4;47(19):10340-10356
Nucleic acids research 2019 Nov 4;47(19):10340-10356
A deafness-associated mitochondrial DNA mutation altered the tRNA(Ser(UCN)) metabolism and mitochondrial function.
Xue L, Chen Y, Tang X, Yao J, Huang H, Wang M, Ye S, Wang M, Guan MX
Mitochondrion 2019 May;46:370-379
Mitochondrion 2019 May;46:370-379
Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement.
Pulman J, Ruzzenente B, Bianchi L, Rio M, Boddaert N, Munnich A, Rötig A, Metodiev MD
Human molecular genetics 2019 May 1;28(9):1445-1462
Human molecular genetics 2019 May 1;28(9):1445-1462
A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.
Jia Z, Zhang Y, Li Q, Ye Z, Liu Y, Fu C, Cang X, Wang M, Guan MX
Nucleic acids research 2019 Feb 28;47(4):2056-2074
Nucleic acids research 2019 Feb 28;47(4):2056-2074
Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability.
Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P
Cell death & disease 2018 Nov 13;9(11):1129
Cell death & disease 2018 Nov 13;9(11):1129
Contribution of the tRNA(Ile) 4317A→G mutation to the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA 1555A→G mutation.
Meng F, He Z, Tang X, Zheng J, Jin X, Zhu Y, Ren X, Zhou M, Wang M, Gong S, Mo JQ, Shu Q, Guan MX
The Journal of biological chemistry 2018 Mar 2;293(9):3321-3334
The Journal of biological chemistry 2018 Mar 2;293(9):3321-3334
A hypertension-associated mitochondrial DNA mutation introduces an m(1)G37 modification into tRNA(Met), altering its structure and function.
Zhou M, Xue L, Chen Y, Li H, He Q, Wang B, Meng F, Wang M, Guan MX
The Journal of biological chemistry 2018 Jan 26;293(4):1425-1438
The Journal of biological chemistry 2018 Jan 26;293(4):1425-1438
Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis.
Ruzzenente B, Assouline Z, Barcia G, Rio M, Boddaert N, Munnich A, Rötig A, Metodiev MD
Human mutation 2018 Dec;39(12):2047-2059
Human mutation 2018 Dec;39(12):2047-2059
A hypertension-associated mitochondrial DNA mutation alters the tertiary interaction and function of tRNA(Leu(UUR)).
Zhou M, Wang M, Xue L, Lin Z, He Q, Shi W, Chen Y, Jin X, Li H, Jiang P, Guan MX
The Journal of biological chemistry 2017 Aug 25;292(34):13934-13946
The Journal of biological chemistry 2017 Aug 25;292(34):13934-13946
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