ABIN197335

antibody from antibodies-online

Targeting: FOXO1 FKH1, FKHR, FOXO1A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN197335

Provider

antibodies-online

Product name

anti-Forkhead Box O1 (FOXO1) (AA 254-258) antibody

Antibody type

Polyclonal

Description

Immunoaffinity Chromatography using epitope-specific immunogen.

Reactivity

Human

Host

Rabbit

Epitope

AA 254-258

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors.

Gan L, Zheng W, Chabot JG, Unterman TG, Quirion R
Journal of neurochemistry 2005 Jun;93(5):1209-19

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Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M
Cell death and differentiation 2005 Jun;12(6):668-77

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Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW
The Journal of cell biology 2005 Apr 25;169(2):331-9

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Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle.

Horn S, Endl E, Fehse B, Weck MM, Mayr GW, Jücker M
Leukemia 2004 Nov;18(11):1839-49

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Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms.

Zhao X, Gan L, Pan H, Kan D, Majeski M, Adam SA, Unterman TG
The Biochemical journal 2004 Mar 15;378(Pt 3):839-49