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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB5362 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB5362, RRID:AB_1574937
- Product name
- FOXO1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of FOXO1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
PKCĪ» haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors.
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Sajan MP, Ivey RA, Lee MC, Farese RV
Journal of lipid research 2015 Jan;56(1):70-80
Journal of lipid research 2015 Jan;56(1):70-80
PKCĪ» haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
Sajan MP, Ivey RA 3rd, Lee M, Mastorides S, Jurczak MJ, Samuels VT, Shulman GI, Braun U, Leitges M, Farese RV
Molecular endocrinology (Baltimore, Md.) 2014 Jul;28(7):1097-107
Molecular endocrinology (Baltimore, Md.) 2014 Jul;28(7):1097-107
Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors.
Gan L, Zheng W, Chabot JG, Unterman TG, Quirion R
Journal of neurochemistry 2005 Jun;93(5):1209-19
Journal of neurochemistry 2005 Jun;93(5):1209-19
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.
Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M
Cell death and differentiation 2005 Jun;12(6):668-77
Cell death and differentiation 2005 Jun;12(6):668-77
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW
The Journal of cell biology 2005 Apr 25;169(2):331-9
The Journal of cell biology 2005 Apr 25;169(2):331-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extract from Hela and NIH/3T3 using FOXO1 polyclonal antibody (Cat # PAB5362) .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FOXO1 polyclonal antibody (Cat # PAB5362) .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
